ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >BOC-amino acid >N-Boc-1-aminocyclobutanecarboxylic acid
N-Boc-1-aminocyclobutanecarboxylic acid
- CAS No.
- 120728-10-1
- Chemical Name:
- N-Boc-1-aminocyclobutanecarboxylic acid
- Synonyms
- BOC-ACBC-OH;BOC-AC4C-OH;BOC-1, 1-ACCB;BOC-CYCLOVALINE;Boc-1-Aminocyclobutanecarboxylic acid;Boc-1-aminocyclobutane-1-carboxylicaci;1-(BOC-AMINO)CYCLOBUTANECARBOXYLIC ACID;N-BOC-1-AMINOCYCLOBUTANE CARBOXYLIC ACID;BOC-1-AMINOCYCLOBUTANE-1-CARBOXYLIC ACID;BOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
- CBNumber:
- CB7110182
- Molecular Formula:
- C10H17NO4
- Molecular Weight:
- 215.25
- MOL File:
- 120728-10-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/9/4 14:12:55
| Melting point | 129-133 °C(lit.) |
|---|---|
| Boiling point | 362.1±21.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 4.14±0.20(Predicted) |
| form | Powder |
| color | White to light brown |
| BRN | 7994003 |
| InChI | InChI=1S/C10H17NO4/c1-9(2,3)15-8(14)11-10(7(12)13)5-4-6-10/h4-6H2,1-3H3,(H,11,14)(H,12,13) |
| InChIKey | ROVVUKFHORPDSM-UHFFFAOYSA-N |
| SMILES | C1(NC(OC(C)(C)C)=O)(C(O)=O)CCC1 |
| CAS DataBase Reference | 120728-10-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H302-H319 | |||||||||
| Precautionary statements | P305+P351+P338-P261-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29242990 | |||||||||
| NFPA 704 |
|
N-Boc-1-aminocyclobutanecarboxylic acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 630802 | N-Boc-1-aminocyclobutane carboxylic acid 97% | 120728-10-1 | 1G | ₹8237.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 630802 | N-Boc-1-aminocyclobutane carboxylic acid 97% | 120728-10-1 | 5G | ₹33654.93 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B6086 | N-tert-Butoxycarbonyl-1-aminocyclobutanecarboxylic Acid min. 98.0 % | 120728-10-1 | 1G | ₹2400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B6086 | N-tert-Butoxycarbonyl-1-aminocyclobutanecarboxylic Acid min. 98.0 % | 120728-10-1 | 5G | ₹8400 | 2022-05-26 | Buy |
N-Boc-1-aminocyclobutanecarboxylic acid Chemical Properties,Uses,Production
Description
N-Boc-1-aminocyclobutanecarboxylic acid (1-((tert-Butoxycarbonyl)amino)cyclobutanecarboxylic acid) is an organic compound used in the preparation of intermediates for Boc-apalutamide. Apalutamide is a prescription drug used to treat prostate cancer.
Synthesis
Under stirring, add 1-aminocyclobutylcarboxylic acid (500mg, 4.34mmol) to 10mL of 0.5M sodium hydroxide solution, and add 10mL of 1,4-dioxane and di-tert-butyl dicarbonate (1.42g, 6.51 mmol), react for 15 hours. Extract with diethyl ether (20 mL × 2), add hydrochloric acid dropwise until the pH of the aqueous phase is 4, and extract with ethyl acetate (30 mL × 3). The organic phases were then combined, washed with saturated sodium chloride solution (20mL×2), dried over anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure to obtain the product N-Boc-1-aminocyclobutanecarboxylic acid (750mg, white solid), yield:80.6%.
N-Boc-1-aminocyclobutanecarboxylic acid Preparation Products And Raw materials
Global( 335)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ALS INDIA LIFE SCIENCES | +91-8977036379 +91-8977036379 | Hyderabad, India | 1879 | 58 | Inquiry |
| RPN ORGANICS PVT LTD | +919010289956 | Telangana, India | 173 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Visa Chem Private Limited | 08048958731 | Hyderabad, India | 59 | 58 | Inquiry |
| RPN Organics Pvt., Ltd. | 91-9010289956 | Telangana, India | 40 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2096 | 58 | Inquiry |
| Sai Carbohydrates | 91-9490021226 | Hyderabad, India | 54 | 58 | Inquiry |
| Visa Chem Pvt. Ltd. | 91-40-64633339 | Hyderabad, India | 48 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ALS INDIA LIFE SCIENCES | 58 |
| RPN ORGANICS PVT LTD | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Visa Chem Private Limited | 58 |
| RPN Organics Pvt., Ltd. | 58 |
| Reax Chemicals | 58 |
| VASIN BIO LIFE SCIENCES PVT LTD | 58 |
| Sai Carbohydrates | 58 |
| Visa Chem Pvt. Ltd. | 58 |
120728-10-1(N-Boc-1-aminocyclobutanecarboxylic acid)Related Search:
N-BOC-1-AMINOCYCLOBUTANE CARBOXYLIC ACID
1-AMINOCYCLOBUTYL-1-CARBOXYLIC ACID, N-BOC PROTECTED
1-(BOC-AMINO)CYCLOBUTANECARBOXYLIC ACID
1-N-BOC-AMINO-CYCLOBUTANE CARBOXYLIC ACID
1-(TERT-BUTYLOXYCARBONYL-AMINO)-CYCLOBUTYL-1-CARBOXYLIC ACID
1-Aminocyclobutane-1-carboxylic acid, N-BOC protected
1-TERT-BUTOXYCARBONYLAMINO-CYCLOBUTANECARBOXYLIC ACID
1-(T-BUTYLOXYCARBONYL-AMINO)-CYCLOBUTYL-1-CARBOXYLIC ACID
BOC-AC4C-OH
BOC-ACBC-OH
BOC-CYCLOVALINE
BOC-1-AMINOCYCLOBUTANE-1-CARBOXYLIC ACID
BOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
BOC-1, 1-ACCB
Boc-1-Aminocyclobutanecarboxylic acid
N-BOC-1-AMINOCYCLOBUTYL-1-CARBOXYLIC ACID
Boc-1-aminocyclobutanecarboxylic acid-OH
1-(Boc-amino)cyclobutanecarboxylic acid, Boc-cyclovaline
Cyclobutanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-
1-[(tert-Butoxycarbonyl)amino]cyclobutane-1-carboxylic acid
1N-1-BOC-Aminocyclobutyl-1-carboxylic acid
1-(tert-butoxycarbonylaMino)cyclobutanecarboxylic axid
1-aMino-2-[(tert-butoxy)carbonyl]cyclobutane-1-carboxylic acid
1-(tert-butoxycarbonyl)cyclobutanecarboxylic acid
1-(tert-butoxycarbonylaMino)cyclobutanecarboxylic
1-[(tert-Butoxycarbonyl)amino]cyclobutane-1-carboxylic acid, tert-Butyl (1-carboxycyclobut-1-yl)carbamate
Boc-1-amino-1-cyclobutane carboxylic acid, 97.5%
1-Aminocyclobutane-1-carboxylic acid, N-BOC protected 97%
Boc-1-aminocyclobutane-1-carboxylicaci
N-tert-Butoxycarbonyl-1-aminocyclobutanecarboxylic Acid
N-Boc-1-aminocyclobutanecarboxylic acid USP/EP/BP
1-(t-Butoxycarbonyl)aminocyclobutanecarboxylic acid
1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclobutane-1-carboxylic acid
N-Boc-1-amino-1-cyclobutane carboxylic acid
N-Boc-amino-1-cyclobutanecarboxylic acid
120728-10-1
20728-10-1
CH33CO2CNHC4H6CO2H
Alicyclic Amino Acids
Unnatural Amino Acid Derivatives
Peptide Synthesis
Specialty Synthesis
Peptide
pharmacetical
Amino Acids and Derivatives
White solid
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