Naproxen sodium
- CAS No.
- 26159-34-2
- Chemical Name:
- Naproxen sodium
- Synonyms
- aleve;Naprelan;Anax;(S)-6-METHOXY-ALPHA-METHYL-2-NAPHTHALENEACETIC ACID SODIUM SALT;Anaprox;NAPROXEN SODIUM SALT;Duk-F;Flanax;RS-3650;Aflaxen
- CBNumber:
- CB8114925
- Molecular Formula:
- C14H13O3.Na
- Molecular Weight:
- 252.24
- MOL File:
- 26159-34-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/13 17:19:14
| Melting point | 250-251°C |
|---|---|
| alpha | D -11° (in methanol) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Freely soluble in water, freely soluble or soluble in methanol, sparingly soluble in ethanol (96 per cent). |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water up to 100mg/mlSoluble in methanol and chloroform. Slightly soluble in ether. Insoluble in water. |
| CAS DataBase Reference | 26159-34-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H360 |
| Precautionary statements | P201-P202-P264-P270-P301+P312-P308+P313 |
| Hazard Codes | Xn,T |
| Risk Statements | 22-61 |
| Safety Statements | 53-45 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | QJ1047000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2918992090 |
Naproxen sodium price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N5160 | Naproxen sodium meets USP testing specifications | 26159-34-2 | 5G | ₹7642.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1165 | Naproxen sodium Pharmaceutical Secondary Standard; Certified Reference Material | 26159-34-2 | 1G | ₹10002.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M1275 | Naproxen sodium 98.0-102.0% | 26159-34-2 | 5G | ₹7837.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N5160 | Naproxen sodium meets USP testing specifications | 26159-34-2 | 50G | ₹34434.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M1275 | Naproxen sodium 98.0-102.0% | 26159-34-2 | 25G | ₹27138.28 | 2022-06-14 | Buy |
Naproxen sodium Chemical Properties,Uses,Production
Chemical Properties
White Powder
Uses
A cyclooxygenase inhibitorNaproxen sodium acts as a nonselective inhibitor of Cox-1 and Cox-2. It serves as an anti-inflammatory agent with analgesic and antipyretic properties. Further, it is used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea and acute gout.
Definition
ChEBI: The sodium salt of naproxen.
General Description
Naproxen sodium (NS) is a sodium salt of propionic acid derivative and demonstrates analgesic, anti-pyretic, and anti-inflammatory properties. It exhibits efficiency in being used as an indomethacin in the treatment of acute musculoskeletal disorders. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDS) and acts by inhibiting the activity of both the cyclooxygenase enzymes, COX-1 & COX-2 and further blocking the synthesis of certain prostaglandins. It is administered in the treatment of ankylosing spondylitis, osteoarthritis, rheumatoid disorders, acute gout, mild to moderate pain, tendonitis, bursitis, dysmenorrhea, fever, and migraine headache. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biological Activity
Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
Naproxen sodium Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ANWITA APIS | +919000311012 | Hyderabad, India | 198 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| Frolic Pharmachem | +919711094561 | Himachal Pradesh, India | 94 | 58 | Inquiry |
| Divis Laboratories Ltd | +91-4066966413 +91-4066966413 | Hyderabad, India | 34 | 58 | Inquiry |
| Granules India Limited | +91-4069043500 +91-4069043500 | Telangana, India | 30 | 58 | Inquiry |
| GRANULES INDIA LTD | +91 40 30660000 | New Delhi, India | 33 | 58 | Inquiry |
| DIVIS LABORATORIES LTD | +91 (40) 6696 6300 | New Delhi, India | 38 | 58 | Inquiry |
| DR REDDYS LABORATORIES LTD | +91-40-49002900 | New Delhi, India | 201 | 58 | Inquiry |
| AUROBINDO PHARMA LTD | +91 (40) 6672 1200 | New Delhi, India | 209 | 58 | Inquiry |
| SOLARA ACTIVE PHARMA SCIENCES LTD | +91 44 4344 6700 | New Delhi, India | 89 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ANWITA APIS | 58 |
| Dr. Reddy's Laboratories Ltd | 58 |
| Frolic Pharmachem | 58 |
| Divis Laboratories Ltd | 58 |
| Granules India Limited | 58 |
| GRANULES INDIA LTD | 58 |
| DIVIS LABORATORIES LTD | 58 |
| DR REDDYS LABORATORIES LTD | 58 |
| AUROBINDO PHARMA LTD | 58 |
| SOLARA ACTIVE PHARMA SCIENCES LTD | 58 |
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