Tubastatin A hydrochloride
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- ₹9900 - ₹81674.63
- Product name: Tubastatin A hydrochloride
- CAS: 1310693-92-5
- MF: C20H22ClN3O2
- MW: 371.87
- EINECS:
- MDL Number:MFCD20488052
- Synonyms:N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride;Tubastatin A hydrochloride;TSA HCl;Tubastatin A Hydrochloride (Also See: T897000);Tubastatin A HCl salt;N-hydroxy-4-((2-methyl-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)benzamide hydrochloride;N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl;Tubastatin A hydrochloride N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberT3687
- Product descriptionTubastatin A Hydrochloride
- Packaging25MG
- Price₹9900
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberT3687
- Product descriptionTubastatin A Hydrochloride
- Packaging100MG
- Price₹34300
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0044
- Product descriptionTubastatin A hydrochloride ≥98% (HPLC)
- Packaging25MG
- Price₹81674.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0044
- Product descriptionTubastatin A hydrochloride ≥98% (HPLC)
- Packaging5MG
- Price₹20762.35
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | T3687 | Tubastatin A Hydrochloride | 25MG | ₹9900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T3687 | Tubastatin A Hydrochloride | 100MG | ₹34300 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML0044 | Tubastatin A hydrochloride ≥98% (HPLC) | 25MG | ₹81674.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0044 | Tubastatin A hydrochloride ≥98% (HPLC) | 5MG | ₹20762.35 | 2022-06-14 | Buy |
Properties
Melting point :>221°C (subl.)
storage temp. :-20°C
solubility :Soluble in DMSO or Water.
form :powder
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
storage temp. :-20°C
solubility :Soluble in DMSO or Water.
form :powder
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Safety Information
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Description
Tubastatin A (1310693-92-5) is a potent and highly selective inhibitor of HDAC6 (IC50?= 15 nM, >1000-fold selectivity against other HDAC isoforms, approx. 60-fold versus HDAC8).1?It displayed anti-inflammatory and anti-rheumatic effects in Freund’s competitive adjuvant induced animal model of inflammation.2?Tubastatin A inhibited TNF-α (IC50?= 272 nM) and IL-6 (IC50 = 712 nM) in LPS stimulated human THP-1 macrophages.2?Tubastatin A has also been shown to have therapeutic potential for treatment of Alzheimer’s disease via altered amyloid-β load and reduced tau hyperphosphorylation.3-5More related product prices
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