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N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide

N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide Structure
  • ₹17612.28 - ₹70925.4
  • Product name: N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
  • CAS: 362003-83-6
  • MF: C25H25N3O2S
  • MW: 431.55
  • EINECS:
  • MDL Number:MFCD01988824
  • Synonyms:adamantane-1-carboxylic acid (2-benzoylamino-benzothiazol-6-yl)amide;N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide;NVP 231;NVP-231;NVP231;CS-1722;NVP-231;NVP 231;NVP231;Tricyclo[3.3.1.13,7]decane-1-carboxamide, N-[2-(benzoylamino)-6-benzothiazolyl]-;NVP231,inhibit,mcf-7,cancer,cerk,Apoptosis,NVP 231,Inhibitor,NCI-H358,NVP-231
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9289
  • Product descriptionNVP-231 ≥98% (HPLC)
  • Packaging5MG
  • Price₹17612.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9289
  • Product descriptionNVP-231 ≥98% (HPLC)
  • Packaging25MG
  • Price₹70925.4
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) N9289 NVP-231 ≥98% (HPLC) 5MG ₹17612.28 2022-06-14 Buy
Sigma-Aldrich(India) N9289 NVP-231 ≥98% (HPLC) 25MG ₹70925.4 2022-06-14 Buy

Properties

Melting point :246-248 °C(Solv: isopropanol (67-63-0); water (7732-18-5))
Density :1.398±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >10mg/mL
pka :9.09±0.70(Predicted)
form :powder
color :white to off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :MVSSJPGNLQPWSW-UHFFFAOYSA-N
SMILES :C12(C(NC3C=C4SC(NC(=O)C5=CC=CC=C5)=NC4=CC=3)=O)CC3CC(CC(C3)C1)C2

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ceramides have diverse roles in cell differentiation, proliferation, and apoptosis. Ceramide kinase converts ceramide to ceramide-1-phosphate (C1P), removing the effects of ceramide in favor of those directed by C1P. NVP-231 is a potent, reversible inhibitor of ceramide kinase (IC50 = 12 nM). It has minimal effect on several other lipid kinases, including sphingosine kinases 1 and 2. In cells in which exogenous short chain ceramide is converted to C1P, resulting in cell death, NVP-231 prevents both C1P synthesis and cell death. In mouse dermal microvascular endothelial cells, where ceramide kinase increases capillary-like tube formation, NVP-231 (100 nM) inhibits C1P formation as well as tube formation.

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Suppliers and manufacturers

career henan chemical co
N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
₹1.00 /1g
N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide CAS:362003-83-6
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