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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >5-HT Receptor agonists >ALMOTRIPTAN

ALMOTRIPTAN

ALMOTRIPTAN Structure
  • ₹5000 - ₹54547.18
  • Product name: ALMOTRIPTAN
  • CAS: 181183-52-8
  • MF: C21H31N3O7S
  • MW: 469.55
  • EINECS:815-382-1
  • MDL Number:MFCD08067740
  • Synonyms:BUTANEDIOIC ACID, HYDROXY-, COMPD WITH 1-[[[3-[2-(DIMETHYLAMINO)ETHYL]-1H-INDOL-5-YL]METHYL]SULFONYL]PYRROLIDINE;ALMOTRIPTAN MALATE;AlmotriptanMaleate;1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine Malate;1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidine Malate;LAS-31416 Malate;Almotriptan;1-[[[3-[2-(dimeth
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 50MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberA3111
  • Product descriptionAlmotriptan Malate
  • Packaging25MG
  • Price₹5000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA3111
  • Product descriptionAlmotriptan Malate
  • Packaging100MG
  • Price₹9200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1210
  • Product descriptionAlmotriptan malate ≥98% (HPLC)
  • Packaging10MG
  • Price₹13563.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1210
  • Product descriptionAlmotriptan malate ≥98% (HPLC)
  • Packaging50MG
  • Price₹54547.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A3111 Almotriptan Malate 25MG ₹5000 2022-05-26 Buy
TCI Chemicals (India) A3111 Almotriptan Malate 100MG ₹9200 2022-05-26 Buy
Sigma-Aldrich(India) SML1210 Almotriptan malate ≥98% (HPLC) 10MG ₹13563.73 2022-06-14 Buy
Sigma-Aldrich(India) SML1210 Almotriptan malate ≥98% (HPLC) 50MG ₹54547.18 2022-06-14 Buy

Properties

Melting point :170-172°C
storage temp. :2-8°C
solubility :Basic Alcohol (Very Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Almotriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s = 12 and 13 nM, respectively, in a radioligand binding assay). It is selective for human 5-HT1B and 5-HT1D receptors over rat 5-HT1A and human 5-HT2A and 5-HT4 receptors (IC50s = 0.85, 25.1, and 140 μM, respectively). Almotriptan induces contractions in isolated canine saphenous veins (EC50 = 394 nM) but not isolated rabbit renal or mesenteric arteries. It increases carotid vascular resistance in anesthetized cats (ED100 = 11 μg/kg, i.v.) without increasing blood pressure or heart rate. Formulations containing almotriptan have been used in the treatment of migraine headaches.

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Suppliers and manufacturers

GLR Innovations Varanous Labs Pvt Ltd SMS Pharmaceuticals Ltd Venkatasai Life Sciences Rivashaa Agrotech Biopharma Pvt. Ltd. Nosch Labs Pvt Ltd Stereokem Pvt Ltd SYNERGENE ACTIVE INGREDIENTS PVT. LIMITED Pharmaffiliates Analytics & Synthetics (P) Ltd. Rensun Pharmaceuticals Pvt Ltd.