Amphotericin B
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- ₹1290 - ₹1557836.58
- Product name: Amphotericin B
- CAS: 1397-89-3
- MF: C47H73NO17
- MW: 924.08
- EINECS:215-742-2
- MDL Number:MFCD00877763
- Synonyms:FUNGIZONE(R);AMPHOTERCIN B;AMPHOTERICIN B;AMPHOTERICIN B SOLUBILIZED;AMPHOTERICIN B, SOLUBLE;AMPHOTERICIN B, STREPTOMYCES NODOSUS;AMPHOTERICIN B, STREPTOMYCES SPECIES;AMPHOZONE
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- Sigma-Aldrich(India)
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- ManufacturerSigma-Aldrich(India)
- Product numberA2942
- Product descriptionAmphotericin B solution 250?μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture
- Packaging20ML
- Price₹3085.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9528
- Product descriptionAmphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture
- Packaging50MG
- Price₹4968.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA2942
- Product descriptionAmphotericin B solution 250?μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture
- Packaging50ML
- Price₹6072.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9528
- Product descriptionAmphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture
- Packaging100MG
- Price₹9493.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4888
- Product descriptionAmphotericin B from Streptomyces sp. ~80% (HPLC), powder
- Packaging100MG
- Price₹10002.3
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA2942
- Product descriptionAmphotericin B solution 250?μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture
- Packaging100ML
- Price₹10554.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4888
- Product descriptionAmphotericin B from Streptomyces sp. ~80% (HPLC), powder
- Packaging100G
- Price₹1557836.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4888
- Product descriptionAmphotericin B from Streptomyces sp. ~80% (HPLC), powder
- Packaging1G
- Price₹50390.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA2411
- Product descriptionAmphotericin B from Streptomyces sp. BioReagent, suitable for cell culture, ~80% (HPLC)
- Packaging1G
- Price₹57329.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9528
- Product descriptionAmphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture
- Packaging1G
- Price₹83677.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4888
- Product descriptionAmphotericin B from Streptomyces sp. ~80% (HPLC), powder
- Packaging5G
- Price₹120482.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA2411
- Product descriptionAmphotericin B from Streptomyces sp. BioReagent, suitable for cell culture, ~80% (HPLC)
- Packaging5G
- Price₹190541.65
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9528
- Product descriptionAmphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture
- Packaging5G
- Price₹319889.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number46006
- Product descriptionAmphotericin B trihydrate VETRANAL?, analytical standard
- Packaging100MG
- Price₹15306.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4888
- Product descriptionAmphotericin B from Streptomyces sp. ~80% (HPLC), powder
- Packaging250MG
- Price₹17027.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA2411
- Product descriptionAmphotericin B from Streptomyces sp. BioReagent, suitable for cell culture, ~80% (HPLC)
- Packaging250MG
- Price₹18142.7
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A2942 | Amphotericin B solution 250?μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture | 20ML | ₹3085.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9528 | Amphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture | 50MG | ₹4968.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2942 | Amphotericin B solution 250?μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture | 50ML | ₹6072.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9528 | Amphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture | 100MG | ₹9493.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A4888 | Amphotericin B from Streptomyces sp. ~80% (HPLC), powder | 100MG | ₹10002.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2942 | Amphotericin B solution 250?μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture | 100ML | ₹10554.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A4888 | Amphotericin B from Streptomyces sp. ~80% (HPLC), powder | 100G | ₹1557836.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A4888 | Amphotericin B from Streptomyces sp. ~80% (HPLC), powder | 1G | ₹50390.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2411 | Amphotericin B from Streptomyces sp. BioReagent, suitable for cell culture, ~80% (HPLC) | 1G | ₹57329.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9528 | Amphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture | 1G | ₹83677.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A4888 | Amphotericin B from Streptomyces sp. ~80% (HPLC), powder | 5G | ₹120482.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2411 | Amphotericin B from Streptomyces sp. BioReagent, suitable for cell culture, ~80% (HPLC) | 5G | ₹190541.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9528 | Amphotericin B solubilized powder, γ-irradiated, BioXtra, suitable for cell culture | 5G | ₹319889.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46006 | Amphotericin B trihydrate VETRANAL?, analytical standard | 100MG | ₹15306.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A4888 | Amphotericin B from Streptomyces sp. ~80% (HPLC), powder | 250MG | ₹17027.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2411 | Amphotericin B from Streptomyces sp. BioReagent, suitable for cell culture, ~80% (HPLC) | 250MG | ₹18142.7 | 2022-06-14 | Buy |
Properties
Melting point :>170°C
Boiling point :804.34°C (rough estimate)
alpha :D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Density :1.34
refractive index :1.5280 (estimate)
storage temp. :2-8°C
solubility :sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20°C. Stable at 37°C for 3 days.
form :powder
pka :pKa ～5.7(DMF/H2O) (Uncertain)
color :yellow
Water Solubility :<0.1 g/100 mL at 21 ºC
Sensitive :Moisture & Light Sensitive
Merck :13,590
BRN :78342
Stability :Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
InChIKey :APKFDSVGJQXUKY-INPOYWNPSA-N
CAS DataBase Reference :1397-89-3(CAS DataBase Reference)
EPA Substance Registry System :Amphotericin B (1397-89-3)
Boiling point :804.34°C (rough estimate)
alpha :D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Density :1.34
refractive index :1.5280 (estimate)
storage temp. :2-8°C
solubility :sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20°C. Stable at 37°C for 3 days.
form :powder
pka :pKa ～5.7(DMF/H2O) (Uncertain)
color :yellow
Water Solubility :<0.1 g/100 mL at 21 ºC
Sensitive :Moisture & Light Sensitive
Merck :13,590
BRN :78342
Stability :Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
InChIKey :APKFDSVGJQXUKY-INPOYWNPSA-N
CAS DataBase Reference :1397-89-3(CAS DataBase Reference)
EPA Substance Registry System :Amphotericin B (1397-89-3)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Amphotericin B is a classic antifungal polyene macrolide that has been used in the treatment of systemic fungal infections, primarily caused by C. albicans, A. fumigatus, and parasitic L. protozoans, as well as in tissue culture to prevent fungi from contaminating cell cultures. Amphotericin B binds with ergosterol, the main component of fungal cell membranes, forming a transmembrane channel that results in altered plasma membrane permeability and leakage of vital cytoplasmic components, such as K+, ultimately inducing cell death. Because prolonged use of amphotericin B is associated with infusion-related events and nephrotoxicity, lipid-based formulations have been devised for more favorable clinical relevance.More related product prices
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