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DPQ

DPQ Structure
  • ₹10500.25 - ₹41903.58
  • Product name: DPQ
  • CAS: 129075-73-6
  • MF: C18H26N2O2
  • MW: 302.41
  • EINECS:
  • MDL Number:MFCD02258932
  • Synonyms:PARP Inhibitor III, DPQ ;DPQ;3,4-DIHYDRO-5-[4-(1-PIPERIDINYL)BUTOXY]-1(2H)-ISOQUINOLINONE;3,4-DIHYDRO-5[4-(1-PIPERIDINYL)BUTOXYL]-1(2H)-ISOQUINOLINE;3,4-DIHYDRO-5-[4-(1-PIPERIDINYL)BUTOXYL]-1(2H)-ISOQUINOLINONE;3,4-DIHYDRO-5[4-(1-PIPERINDINYL)BUTOXY]-1(2H)-ISOQUINOLINE;5-[4-(1-PIPERIDINYL)-BUTYLOXY]-1,2,3,4-TETRAHYDROISOQUINOLIN-1-ONE;DMEM(Low Glucose)
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5314
  • Product descriptionDPQ ≥98% (HPLC), solid
  • Packaging1MG
  • Price₹10500.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number300270
  • Product descriptionPARP Inhibitor III, DPQ - CAS 129075-73-6 - Calbiochem The PARP Inhibitor III, DPQ, also referenced under CAS 129075-73-6, controls the biological activity of PARP. This small molecule/inhibitor is primari
  • Packaging1MG
  • Price₹13100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5314
  • Product descriptionDPQ ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹41903.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D5314 DPQ ≥98% (HPLC), solid 1MG ₹10500.25 2022-06-14 Buy
Sigma-Aldrich(India) 300270 PARP Inhibitor III, DPQ - CAS 129075-73-6 - Calbiochem The PARP Inhibitor III, DPQ, also referenced under CAS 129075-73-6, controls the biological activity of PARP. This small molecule/inhibitor is primari 1MG ₹13100 2022-06-14 Buy
Sigma-Aldrich(India) D5314 DPQ ≥98% (HPLC), solid 5MG ₹41903.58 2022-06-14 Buy

Properties

Melting point :107-109°
Boiling point :528.8±50.0 °C(Predicted)
Density :1.096±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: Soluble
form :solid
pka :14.54±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can be used in either cells or in animals.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD.
SUZHOU SENFEIDA CHEMICAL CO.,LTD
Aladdin Scientific Changsha Fuzhen Biotechnology Co.，LTD RD International Technology Co., Limited Beijing Dongge Boye Biotechnology Co., Ltd. Shanghai Yiyan Biological Technology Co., Ltd. Shanghai Heguo Biological Technology Co., Ltd. Energy Chemical Creative Enzymes