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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >DNA damage >PARP inhibitors >NU1025

NU1025

NU1025 Structure
  • ₹20250 - ₹24583.58
  • Product name: NU1025
  • CAS: 90417-38-2
  • MF: C9H8N2O2
  • MW: 176.17
  • EINECS:
  • MDL Number:MFCD00942555
  • Synonyms:NU1025;8-HYDROXY-2-METHYL-4(3H)-QUINAZOLINONE;8-HYDROXY-2-METHYLQUINAZOLIN-4[3H]-ONE;8-HYDROXY-2-METHYLQUINAZOLINE-4-ONE;8-Hydroxy-2-methylquinazoline-4-one ,97%;8-hydroxy-2-methyl-1H-quinazolin-4-one;NSC 696807;4(3H)-Quinazolinone, 8-hydroxy-2-Methyl-
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7287
  • Product descriptionNU-1025 ≥97% (HPLC), solid
  • Packaging5MG
  • Price₹24583.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number493800
  • Product descriptionPARP Inhibitor VI, NU1025 - CAS 90417-38-2 - Calbiochem The PARP Inhibitor VI, NU1025, also referenced under CAS 90417-38-2, controls the biological activity of PARP. This small molecule/inhibitor is primar
  • Packaging5MG
  • Price₹20250
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) N7287 NU-1025 ≥97% (HPLC), solid 5MG ₹24583.58 2022-06-14 Buy
Sigma-Aldrich(India) 493800 PARP Inhibitor VI, NU1025 - CAS 90417-38-2 - Calbiochem The PARP Inhibitor VI, NU1025, also referenced under CAS 90417-38-2, controls the biological activity of PARP. This small molecule/inhibitor is primar 5MG ₹20250 2022-06-14 Buy

Properties

Melting point :253-258°C
Boiling point :345.4±44.0 °C(Predicted)
Density :1.42
storage temp. :−20°C
solubility :DMSO: 35 mg/mL, soluble
form :solid
pka :8.68±0.20(Predicted)
color :off-white
CAS DataBase Reference :90417-38-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NU 1025 is an inhibitor of poly(ADP-ribose) polymerases (PARP) (IC50 = 400 nM). It enhances the cytotoxicity of γ-irradiation and certain anticancer drugs. NU 1025 is also used to study the regulation of deoxyribonucleic acid repair by PARP enzymes.

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