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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Entecavir

Entecavir

Entecavir Structure
  • ₹7015.2 - ₹28371.6
  • Product name: Entecavir
  • CAS: 142217-69-4
  • MF: C12H15N5O3
  • MW: 277.28
  • EINECS:604-279-5
  • MDL Number:MFCD00907887
  • Synonyms:Aids098045;Aids-098045;Enticavir;EntikaweiPian;2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3H-purin-6(9H)-one ,99.7%;(1S,3R,4S)-9-[4-Hydroxy-3-(hydroxyMethyl)-2-Methylenecyclopentyl]guanine;Entecavir Anhydrous;20MG/100MG/100G
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1103
  • Product descriptionEntecavir ≥98% (HPLC)
  • Packaging10MG
  • Price₹7015.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1103
  • Product descriptionEntecavir ≥98% (HPLC)
  • Packaging50MG
  • Price₹28371.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1103 Entecavir ≥98% (HPLC) 10MG ₹7015.2 2022-06-14 Buy
Sigma-Aldrich(India) SML1103 Entecavir ≥98% (HPLC) 50MG ₹28371.6 2022-06-14 Buy

Properties

Melting point :249-252°C
Boiling point :661.4±65.0 °C(Predicted)
Density :1.81±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Sparingly)
pka :14.22±0.60(Predicted)
form :powder
color :white to beige
optical activity :[α]/D +25 to +40°, c = 0.2 in H2O
Stability :Hygroscopic
CAS DataBase Reference :142217-69-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.

Description

Entecavir is a cyclopentyl guanosine analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection, and it is the third nucleoside or nucleotide analog to be marketed for this indication. Lamivudine, a deoxythiacytosine analog, and adefovir dipivoxil, a nucleotide analog, have been marketed since 1998 and 2002, respectively. Entecavir and adefovir are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections.

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