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H-9 DIHYDROCHLORIDE

H-9 DIHYDROCHLORIDE Structure
  • ₹0
  • Product name: H-9 DIHYDROCHLORIDE
  • CAS: 116700-36-8
  • MF: C11H15Cl2N3O2S
  • MW: 324.23
  • EINECS:
  • MDL Number:MFCD00069286
  • Synonyms:H-9 DIHYDROCHLORIDE;H-9;N-(2-AMINOETHYL)ISOQUINOLINE-5-SULPHONAMIDE DIHYDROCHLORIDE;N-(2-AMINOETHYL)-5-ISOQUINOLINESULFONAMIDE 2HCL;N-(2-AMINOETHYL)-5-ISOQUINOLINESULFONAMIDE DIHYDROCHLORIDE;N-(2-aminoethyl)-5-isoquinoline-*sulfonamide hydr;HBLCYSFLYMHCBM-UHFFFAOYSA-N;Fasudil Impurity 23 DiHCl
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :250-255°C dec.
storage temp. :−20°C
solubility :Soluble to 100 mM in water and to 100 mM in DMSO
form :Powder
color :Light yellow to yellow
CAS DataBase Reference :116700-36-8(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The H series isoquinolinesulfonamide protein kinase inhibitors are widely used to block signaling pathways in order to elucidate mechanisms of cellular regulation and signal transduction. H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA with Ki values of 18, 0.87, and 1.9 μM, respectively. H-9 (hydrochloride) has been used to reduce the cAMP-mediated excitatory response to serotonin in C. elegans enteric neurons and to inhibit PKA-mediated phosphorylation in a rat seizure model.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD.
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
Aladdin Scientific Shanghai Aladdin Biochemical Technology Co.,Ltd. Changsha Fuzhen Biotechnology Co.，LTD Wuhan Acumen Bio-Technology Co.,ltd Suzhou Zhixin Biotechnology Co., Ltd. Cayman Chemical Company Shanghai Yifei Biotechnology Co. , Ltd.