PF-9366
|
- ₹0
- Product name: PF-9366
- CAS: 72882-78-1
- MF: C20H19ClN4
- MW: 350.84
- EINECS:-0
- MDL Number:MFCD31630724
- Synonyms:PF-9366;CS-2703;PF-9366; PF 9366; PF9366;72882-78-1;PF 9366 NEW;[1,2,4]Triazolo[4,3-a]quinoline-1-ethanamine, 7-chloro-N,N-dimethyl-5-phenyl-;2-(7-Chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine;PF-9366,inhibit,PF9366,PF 9366,Inhibitor
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|
Properties
Melting point :182-183.5 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml).
pka :8.75±0.28(Predicted)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml).
pka :8.75±0.28(Predicted)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
PF-9366 (72882-78-1) is an allosteric inhibitor (IC50?= 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1?It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 μM and 225 nM respectively.More related product prices
PF 573228 1144035-53-9 PF-3450074 PF06869206 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione 947303-87-9 PF-6274484 PF-562271 PF-06281355 PF-05212384 PF-3758309 6-chloro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylicacid 717906-29-1 PF 05105679 PI-3065 PFI-2 (hydrochloride) Oclacitinib PF-06447475 PF 543 PF-06282999Related product price
- PF 573228
₹14667.88-59948.85 - 1144035-53-9
₹11506.98-46374.3 - PF-3450074
₹11550.28-46558.33