SPLITOMICIN
- ₹7800 - ₹19050
- Product name: SPLITOMICIN
- CAS: 5690-03-9
- MF: C13H10O2
- MW: 198.22
- EINECS:
- MDL Number:MFCD08705254
- Synonyms:SPLITOMICIN;1,2-DIHYDRO-3H-NAPHTHO[2,1-B]PYRAN-3-ONE;2-Hydroxy-1-naphthalenepropanoic acid delta-lactone;Splitomycin;1H-Benzo[f]chromen-3(2H)-one;Splitomicin >Spitomicin;1,2-Dihydro-3H-benzo[f]chromen-3-one
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberS0892
- Product descriptionSplitomicin min. 98.0 %
- Packaging200MG
- Price₹7800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberS0892
- Product descriptionSplitomicin min. 98.0 %
- Packaging1G
- Price₹17500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number567750
- Product descriptionSplitomicin - CAS 5690-03-9 - Calbiochem A cell-permeable lactone derived from β-naphthol that acts as a selective inhibitor of NAD+-dependent histone deacetylase activity of Sir2 protein (IC
- Packaging5MG
- Price₹19050
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS4068
- Product descriptionSplitomicin ≥98% (HPLC), powder
- Packaging5MG
- Price₹9190.43
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | S0892 | Splitomicin min. 98.0 % | 200MG | ₹7800 | 2022-05-26 | Buy |
TCI Chemicals (India) | S0892 | Splitomicin min. 98.0 % | 1G | ₹17500 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | 567750 | Splitomicin - CAS 5690-03-9 - Calbiochem A cell-permeable lactone derived from β-naphthol that acts as a selective inhibitor of NAD+-dependent histone deacetylase activity of Sir2 protein (IC | 5MG | ₹19050 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S4068 | Splitomicin ≥98% (HPLC), powder | 5MG | ₹9190.43 | 2022-06-14 | Buy |
Properties
Melting point :73-74.5℃
storage temp. :2-8°C
solubility :insoluble in H2O; ≥44.2 mg/mL in EtOH with ultrasonic; ≥9.05 mg/mL in DMSO
form :solid
color :White to Almost white
storage temp. :2-8°C
solubility :insoluble in H2O; ≥44.2 mg/mL in EtOH with ultrasonic; ≥9.05 mg/mL in DMSO
form :solid
color :White to Almost white
Safety Information
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Description
Sir2p, the product of the SIR2 gene, is a conserved NAD+-dependent histone deacetylase (HDAC) involved in the regulation of the lifespan in yeast. It plays roles in silencing gene expression and negatively regulates the initiation of DNA replication. Splitomicin is a small molecule inhibitor of Sir2p histone deacetylase activity, displaying higher activity in vivo (minimal inhibitory concentration = 0.49 μM) than in vitro (IC50 = 60 μM). It less effectively inhibits yeast Hst1, a paralog of Sir2p. Splitomicin has diverse effects on mammalian cells.More related product prices
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