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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Voglibose

Voglibose

Voglibose Structure
  • ₹4870 - ₹24616.05
  • Product name: Voglibose
  • CAS: 83480-29-9
  • MF: C10H21NO7
  • MW: 267.28
  • EINECS:1312995-182-4
  • MDL Number:MFCD00865496
  • Synonyms:Voglistat;epi-Inositol, 2,3-dideoxy-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-4-C-(hydroxymethyl)-;2,3-Dideoxy-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-4-C-(hydroxymethyl)-epi-inositol;Beigrace;Jumeal;Voglibose ,98%;3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol;N-(1,3-Dihydroxyprop-2-yl)valiolamine
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 10MG
  • 100MG
  • 500mg
  • ManufacturerTCI Chemicals (India)
  • Product numberV0119
  • Product descriptionVoglibose
  • Packaging100MG
  • Price₹10900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number50359
  • Product descriptionVoglibose ≥97.0% (TLC)
  • Packaging10MG
  • Price₹24616.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number40996
  • Product descriptionVoglibose extrapure, 98%
  • Packaging100mg
  • Price₹4870
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number40996
  • Product descriptionVoglibose extrapure, 98%
  • Packaging500mg
  • Price₹16230
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) V0119 Voglibose 100MG ₹10900 2022-05-26 Buy
Sigma-Aldrich(India) 50359 Voglibose ≥97.0% (TLC) 10MG ₹24616.05 2022-06-14 Buy
SRL 40996 Voglibose extrapure, 98% 100mg ₹4870 2022-05-26 Buy
SRL 40996 Voglibose extrapure, 98% 500mg ₹16230 2022-05-26 Buy

Properties

Melting point :162-163°C
alpha :D25 +26.2° (c = 1 in water)
Boiling point :601.9±55.0 °C(Predicted)
Density :1.58±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Very Slightly, Heated), Water (Sparingly, Sonicated)
form :Solid
pka :13.26±0.70(Predicted)
color :White to Off-White
Merck :14,10029
InChIKey :FZNCGRZWXLXZSZ-CIQUZCHMSA-N
CAS DataBase Reference :83480-29-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Voglibose is a competitive α-glucosidase inhibitor (IC50 = 5.6 μM) that was first isolated from S. hygroscopicus. It has been shown to delay the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase, isomaltase, and sucrase with IC50 values of 0.18, 5.2, and 0.37 μM, respectively. Voglibose is also reported to increase glucagon-like peptide 1 release. In clinical trials, voglibose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.

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