Entecavir hydrate
- ₹8500 - ₹29500
- Product name: Entecavir hydrate
- CAS: 209216-23-9
- MF: C12H17N5O4
- MW: 295.3
- EINECS:606-668-5
- MDL Number:MFCD09754448
- Synonyms:entecavir hydrate;ENTECAVIR MONOHYDRATE;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;Entecavir hydrate / 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate ,99.9%;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate ,99.7%;Entecavir Monohydrate IsoMers;2-aMino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxyMethyl)-2-Methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one
2 prices
Selected condition:
Brand
- TCI Chemicals (India)
Package
- 50MG
- 200MG
- ManufacturerTCI Chemicals (India)
- Product numberE0899
- Product descriptionEntecavir Monohydrate
- Packaging200MG
- Price₹29500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberE0899
- Product descriptionEntecavir Monohydrate
- Packaging50MG
- Price₹8500
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | E0899 | Entecavir Monohydrate | 200MG | ₹29500 | 2022-05-26 | Buy |
TCI Chemicals (India) | E0899 | Entecavir Monohydrate | 50MG | ₹8500 | 2022-05-26 | Buy |
Properties
Melting point :>220°
alpha :D +35.0° (c = 0.38 in water)
Density :1.81
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Sparingly), Water (Slightly, Heated, Sonicated)
form :Solid
color :White to Off-White
Merck :14,3595
InChI :InChI=1/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/s3
InChIKey :YXPVEXCTPGULBZ-UQHDSAJHNA-N
SMILES :C=C1[C@@H]([C@@H](O)C[C@@H]1N1C=NC2C(NC(N)=NC1=2)=O)CO.O |&1:2,3,6,r|
CAS DataBase Reference :209216-23-9(CAS DataBase Reference)
alpha :D +35.0° (c = 0.38 in water)
Density :1.81
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Sparingly), Water (Slightly, Heated, Sonicated)
form :Solid
color :White to Off-White
Merck :14,3595
InChI :InChI=1/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/s3
InChIKey :YXPVEXCTPGULBZ-UQHDSAJHNA-N
SMILES :C=C1[C@@H]([C@@H](O)C[C@@H]1N1C=NC2C(NC(N)=NC1=2)=O)CO.O |&1:2,3,6,r|
CAS DataBase Reference :209216-23-9(CAS DataBase Reference)
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
Entecavir is a potent deoxyguanosine nucleoside analog with antiviral activity selective for hepadnaviruses (EC50 = 3.7 nM against the hepatitis B virus (HBV) in cultured 2.2.15 liver cells). In vitro, the active intracellular form of entecavir, entecavir triphosphate, demonstrates a higher binding affinity for HBV DNA polymerase than the natural guanosine triphosphate substrate and effectively inhibits HBV DNA replication at 3 stages in the replication pathway: priming, reverse transcription, and DNA-dependent DNA synthesis. The potential therapeutic bene?ts of entecavir have been demonstrated in woodchuck and duck models of HBV. Activity was con?rmed in phase I/II preclinical studies and entecavir received approval from the U.S. Food and Drug Administration for the treatment of adults with chronic hepatitis B.More related product prices
CHLOROPHOSPHONAZO III 3-Aminophenol Glycine 6-Methoxyguanine Entecavir Chloral hydrate 6-Thioguanine Guanine Tris Base 6-Aminocaproic acid Trimethylol propane Entacapone 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine Entecavir hydrateRelated product price
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