LMK-235
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- ₹9536.83 - ₹38818.45
- Product name: LMK-235
- CAS: 1418033-25-6
- MF: C15H22N2O4
- MW: 294.35
- EINECS:808-770-7
- MDL Number:MFCD26522892
- Synonyms:N-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide;N-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethylbenzamide LMK-235;LMK-235;CS-1820;LMK235; LMK 235;Benzamide, N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1053
- Product descriptionLMK235 ≥98% (HPLC)
- Packaging5MG
- Price₹9536.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1053
- Product descriptionLMK235 ≥98% (HPLC)
- Packaging25MG
- Price₹38818.45
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1053 | LMK235 ≥98% (HPLC) | 5MG | ₹9536.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1053 | LMK235 ≥98% (HPLC) | 25MG | ₹38818.45 | 2022-06-14 | Buy |
Properties
Melting point :135-138°C
Density :1.155±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :9.46±0.20(Predicted)
color :white to beige
InChIKey :VRYZCEONIWEUAV-UHFFFAOYSA-N
Density :1.155±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :9.46±0.20(Predicted)
color :white to beige
InChIKey :VRYZCEONIWEUAV-UHFFFAOYSA-N
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues, which commonly results in chromatin condensation and transcriptional repression. LMK 235 is an HDAC inhibitor that selectively targets HDACs 4 and 5 (IC50s = 12 and 4 nM, respectively) over other HDACs (IC50s = 56, 320, 850, 880, and 1,280 for HDACs 6, 1, 11, 2, and 8, respectively). It displays enhanced cytotoxic effects against human cancer cell lines, compared to SAHA or trichostatin A . LMK 235 and derivatives inhibit the growth of the malarial parasite P. falciparum at multiple life cycle stages at nanomolar concentrations.More related product prices
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