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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Lipid regulating drugs >Mevastatin

Mevastatin

Mevastatin Structure
  • ₹2800 - ₹23076
  • Product name: Mevastatin
  • CAS: 73573-88-3
  • MF: C23H34O5
  • MW: 390.51
  • EINECS:700-442-0
  • MDL Number:MFCD05662341
  • Synonyms:Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-;,8-beta(2s*,4s*),8a-beta))- ;antibioticml236b ;butanoicacid,2-methyl-,1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hy ;compactin(penicillium) ;(S)-2-Methylbutyric acid [(1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1-yl] ester;2-Methyl-butanoic acid [1S-[1-α(R*),7-β,8-β(2S*,4S*),8a-β]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester;Mevastatin, >=97%
Price9 Properties Safety Information Description
9 prices
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Brand

  • Sigma-Aldrich
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 5MG
  • 10mg
  • 25mg
  • 50MG
  • 100MG
  • 1G
  • 5G
  • ManufacturerSigma-Aldrich
  • Product number474700
  • Product descriptionMevastatin - CAS 73573-88-3 - Calbiochem An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation.
  • Packaging50MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2275
  • Product descriptionMevastatin
  • Packaging100MG
  • Price₹2800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2275
  • Product descriptionMevastatin
  • Packaging1G
  • Price₹11700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2275
  • Product descriptionMevastatin
  • Packaging5G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2537
  • Product descriptionMevastatin ≥98% (HPLC), powder or crystals
  • Packaging5MG
  • Price₹14938.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number474700
  • Product descriptionMevastatin - CAS 73573-88-3 - Calbiochem An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation.
  • Packaging50MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J61357-MB
  • Product descriptionMevastatin, 98%
  • Packaging25mg
  • Price₹23076
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J61357-MA
  • Product descriptionMevastatin, 98%
  • Packaging10mg
  • Price₹15092
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J61357-LB0
  • Product descriptionMevastatin, 98%
  • Packaging5mg
  • Price₹3176
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 474700 Mevastatin - CAS 73573-88-3 - Calbiochem An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation. 50MG ₹15469.99 2022-06-14 Buy
TCI Chemicals (India) M2275 Mevastatin 100MG ₹2800 2022-05-26 Buy
TCI Chemicals (India) M2275 Mevastatin 1G ₹11700 2022-05-26 Buy
TCI Chemicals (India) M2275 Mevastatin 5G ₹19500 2022-05-26 Buy
Sigma-Aldrich(India) M2537 Mevastatin ≥98% (HPLC), powder or crystals 5MG ₹14938.5 2022-06-14 Buy
Sigma-Aldrich(India) 474700 Mevastatin - CAS 73573-88-3 - Calbiochem An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation. 50MG ₹15469.99 2022-06-14 Buy
ALFA India ALF-J61357-MB Mevastatin, 98% 25mg ₹23076 2022-05-26 Buy
ALFA India ALF-J61357-MA Mevastatin, 98% 10mg ₹15092 2022-05-26 Buy
ALFA India ALF-J61357-LB0 Mevastatin, 98% 5mg ₹3176 2022-05-26 Buy

Properties

Melting point :151-153 °C
alpha :D22 +283° (c = 0.48 in acetone)
Boiling point :555.0±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :DMSO: 20 mg/mL
pka :13.49±0.40(Predicted)
form :powder
color :white
λmax :246nm(MeOH)(lit.)
Merck :14,6164
BRN :1269441
InChIKey :AJLFOPYRIVGYMJ-INTXDZFKSA-N
CAS DataBase Reference :73573-88-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) , induces apoptosis which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
Mevastatin
₹0.00 /25KG
Mevastatin CAS:73573-88-3
OCEAN TRADING CORPORATION BIOCON LTD TCI Chemicals (India) Pvt. Ltd. CLEARSYNTH LABS LTD. A.J Chemicals Alfa Aesar Pharmaffiliates Analytics and Synthetics P. Ltd Triveni chemicals SynZeal Research Pvt Ltd