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ML213

ML213 Structure
  • ₹9536.83 - ₹37638.53
  • Product name: ML213
  • CAS: 489402-47-3
  • MF: C17H23NO
  • MW: 257.37
  • EINECS:803-886-4
  • MDL Number:MFCD00848936
  • Synonyms:N-(2,4,6-TriMethylphenyl)-bicyclo[2.2.1]heptane-2-carboxaMide;CID 3111211;CID3111211;ML213;ML 213;CID 3111211;CID3111211;CS-2507;ML-213(CID-3111211);Bicyclo[2.2.1]heptane-2-carboxamide, N-(2,4,6-trimethylphenyl)-
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0611
  • Product descriptionML213 ≥98% (HPLC)
  • Packaging5MG
  • Price₹9536.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0611
  • Product descriptionML213 ≥98% (HPLC)
  • Packaging25MG
  • Price₹37638.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0611 ML213 ≥98% (HPLC) 5MG ₹9536.83 2022-06-14 Buy
Sigma-Aldrich(India) SML0611 ML213 ≥98% (HPLC) 25MG ₹37638.53 2022-06-14 Buy

Properties

Boiling point :398.8±11.0 °C(Predicted)
Density :1.106±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :14.79±0.70(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The KCNQ (Kv7) family of voltage-gated potassium (K+) channels consists of five members, KCNQ1-KCNQ5. KCNQ1-KCNQ5 are critical for setting up the excitation threshold of action potentials. KCNQ1 is expressed mainly in cardiac tissue, peripheral epithelial cells, and smooth muscle cells, while KCNQ2-KCNQ5 are predominantly expressed in the peripheral and central nervous system, including hippocampal cells, cortical cells, and dorsal root ganglion. ML-213 is a selective activator of KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) channels (EC50s = 230 and 510 nM for KCNQ2 and KCNQ4, respectively) that demonstrates > 80-fold selectivity against other related K+ channels.

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