ML234
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- ₹13000.83 - ₹52360.53
- Product name: ML234
- CAS: 1222800-79-4
- MF: C21H23N3O2
- MW: 349.43
- EINECS:
- MDL Number:MFCD28053518
- Synonyms:ML234;ML324;N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide;NCGC00183808-01;ML324(CID-44143209);CS-2198;ML-324;ML324;ML 324;Benzamide, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0741
- Product descriptionML324 ≥98% (HPLC)
- Packaging25MG
- Price₹52360.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0741
- Product descriptionML324 ≥98% (HPLC)
- Packaging5MG
- Price₹13000.83
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0741 | ML324 ≥98% (HPLC) | 25MG | ₹52360.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0741 | ML324 ≥98% (HPLC) | 5MG | ₹13000.83 | 2022-06-14 | Buy |
Properties
Melting point :>187oC (dec.)
Boiling point :590.1±50.0 °C(Predicted)
Density :1.188±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.71±0.40(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :590.1±50.0 °C(Predicted)
Density :1.188±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.71±0.40(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
The family of Jumonji domain containing histone demethylases 2 (JMJD2s, also known as KDM4s) demethylates lysines 9 and 36 on histone 3, resulting in the repression of specific mammalian and viral genes. ML-324 is a cell-permeable inhibitor of JMJD2E (KDM4DL; IC50 = 920 nM) that is inactive against lysine-specific demethylase, LSD1. It reduces the expression of immediate early genes of Herpes simplex virus (IC50 = ~10 μM) and human cytomegalovirus, blocks viral infection, and suppresses the level of viral reactivation in a ganglia explant model of latently infected mice. The effects of ML-324 are reversible, as viral replication resumes after drug withdrawal.Related product price
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