ML277
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- ₹12394.63 - ₹50076.45
- Product name: ML277
- CAS: 1401242-74-7
- MF: C23H25N3O4S2
- MW: 471.59
- EINECS:
- MDL Number:MFCD28133374
- Synonyms:VU0458298-2, VU0458298-3;ML277;(2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide;(R)-N-(4-(4-Methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide;CID-53347902;ML277;ML 277; ML-277;(2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-[(4-methylphenyl) sulfonyl]-2-piperidinecarboxamide;(2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0524
- Product descriptionML277 ≥98% (HPLC)
- Packaging5MG
- Price₹12394.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0524
- Product descriptionML277 ≥98% (HPLC)
- Packaging25MG
- Price₹50076.45
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0524 | ML277 ≥98% (HPLC) | 5MG | ₹12394.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0524 | ML277 ≥98% (HPLC) | 25MG | ₹50076.45 | 2022-06-14 | Buy |
Properties
Density :1.341±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 5 mg/ml
pka :8.37±0.70(Predicted)
form :powder
color :white to beige
storage temp. :2-8°C
solubility :DMSO: 5 mg/ml
pka :8.37±0.70(Predicted)
form :powder
color :white to beige
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Potassium (K+) channels are categorized by their mode of activation and the number of transmembrane segments. The voltage-gated six-transmembrane K+ channels include KCNQ1, first recognized for its role in cardiac function and subsequently in hearing, gastrointestinal chloride secretion, and other processes. ML-277 is a potent activator of KCNQ1 channels (EC50 = 260 nM). The EC50 value of this compound at the related channels KCNQ2, KCNQ4, and hERG exceeds 30 μM. ML-277 potentiates both homomultimeric KCNQ1 channels and unsaturated heteromultimeric (KCNQ1/KCNE1) channels in model cardiomyocytes and augments delayed rectifier K+ current in cultured human cardiomyocytes.More related product prices
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Suppliers and manufacturers
career henan chemical co
![(2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-[(4-methylphenyl) sulfonyl]-2-piperidinecarboxamide](https://img.chemicalbook.com/ProductImageEN/2020-1/small/a543bc69-dbce-4a42-ad85-a196fde9ef04.png)
CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
₹1.00 /1KG
(2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-[(4-methylphenyl) sulfonyl]-2-piperidinecarboxamide CAS:1401242-74-7
(2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-[(4-methylphenyl) sulfonyl]-2-piperidinecarboxamide CAS:1401242-74-7
