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SIGUAZODAN

SIGUAZODAN Structure
CAS No.
115344-47-3
Chemical Name:
SIGUAZODAN
Synonyms
SKF 94836;SIGUAZODAN;SK AND F-94836;Siguazodan (SKF 94836);SKF-94836,inhibit,Phosphodiesterase (PDE),SKF94836,Siguazodan,Inhibitor;N-Cyano-Nmethyl-Nⅱ-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine;N-CYANO-N'-METHYL-N''-[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL]GUANIDINE;Guanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-;4β-Methyl-4,5-dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]pyridazin-6(1H)-one;Siguazodan, N-Cyano-Nμ-methyl-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
CBNumber:
CB6229034
Molecular Formula:
C14H16N6O
Molecular Weight:
284.32
MOL File:
115344-47-3.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:05
Request For Quotation

SIGUAZODAN Properties

Melting point 268-268.9 °C(lit.)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >5 mg/mL, freely soluble
pka 13.71±0.60(Predicted)
form solid
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

SIGUAZODAN Chemical Properties,Uses,Production

Uses

Siguazodan is a selective phosphodiesterase PDE III inhibitor and a potent inotropic agent.

Biological Activity

Phosphodiesterase inhibitor, selective for PDE3 (IC 50 = 117 nM).

SIGUAZODAN Preparation Products And Raw materials

Raw materials

Preparation Products

SIGUAZODAN Suppliers

Global( 58)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. +86-027-59232304 15387063101 China 9915 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9274 58 Inquiry
InvivoChem 13549236410 China 6747 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9650 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4551 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 China 9929 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. 58
RD International Technology Co., Limited 58
InvivoChem 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58
Shanghai EFE Biological Technology Co., Ltd. 58
Nantong QuanYi Biotechnology Co., Ltd 58
BOC Sciences 65
Shanghai Chaolan Chemical Technology Center 58

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SIGUAZODAN SK AND F-94836 SKF 94836 N-CYANO-N'-METHYL-N''-[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL]GUANIDINE N-Cyano-Nmethyl-Nⅱ-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine Siguazodan, N-Cyano-Nμ-methyl-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine Siguazodan (SKF 94836) [4R,(-)]-4,5-Dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]-4-methylpyridazin-6(1H)-one [4S,(+)]-4,5-Dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]-4-methylpyridazin-6(1H)-one 4β-Methyl-4,5-dihydro-3-[4-[[(cyanoimino)(methylamino)methyl]amino]phenyl]pyridazin-6(1H)-one Guanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]- SKF-94836,inhibit,Phosphodiesterase (PDE),SKF94836,Siguazodan,Inhibitor 115344-47-3 C14H16N6O Cell Biology Cell Signaling and Neuroscience BioChemical G Proteins and Cyclic Nucleotides Phosphodiesterase Inhibitors Cyclic Nucleotide Metabolism Cyclic Nucleotide related