2-PHENYLPROPIONIC ACID
![2-PHENYLPROPIONIC ACID Structure](CAS/GIF/492-37-5.gif)
- CAS No.
- 492-37-5
- Chemical Name:
- 2-PHENYLPROPIONIC ACID
- Synonyms
- HYDRATROPIC ACID;Benzeneacetic acid, .alpha.-methyl-;2-Phenylproplonic Acid;(±)-α-methylphenylaceticacid;(±)-2-Phenylpropionic acid, (±)-Hydratropic acid;dl-PPA;2-Phenylpropionic;RARECHEM AL BO 0089;TIMTEC-BB SBB007855;DL-HYDRATROPIC ACID
- CBNumber:
- CB9293539
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.18
- MOL File:
- 492-37-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/16 18:25:32
Melting point | 5 °C |
---|---|
Boiling point | 260-262 °C (lit.) |
Density | 1.1 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | >230 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | 9.9g/l |
form | Liquid |
pka | 4.34±0.10(Predicted) |
color | Clear pale yellow to yellow |
PH | 3 (5g/l, H2O, 20℃) |
Water Solubility | 10 g/L (20 ºC) |
BRN | 1863558 |
LogP | 1.699 (est) |
CAS DataBase Reference | 492-37-5(CAS DataBase Reference) |
NIST Chemistry Reference | Benzeneacetic acid, «alpha»-methyl-(492-37-5) |
EPA Substance Registry System | Benzeneacetic acid, .alpha.-methyl- (492-37-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS05 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H314 | |||||||||
Precautionary statements | P280-P303+P361+P353-P305+P351+P338+P310 | |||||||||
Hazard Codes | Xi,C | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29163900 | |||||||||
NFPA 704 |
|
2-PHENYLPROPIONIC ACID price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P31701 | 2-Phenylpropionic acid 97% | 492-37-5 | 5G | ₹1937.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P31701 | 2-Phenylpropionic acid 97% | 492-37-5 | 10G | ₹3561.43 | 2022-06-14 | Buy |
TCI Chemicals (India) | P0699 | DL-2-Phenylpropionic Acid min. 98.0 % | 492-37-5 | 5G | ₹2100 | 2022-05-26 | Buy |
ALFA India | ALF-L00709-22 | (+/-)-2-Phenylpropionic acid, 98% | 492-37-5 | 100g | ₹32071 | 2022-05-26 | Buy |
TCI Chemicals (India) | P0699 | DL-2-Phenylpropionic Acid min. 98.0 % | 492-37-5 | 25G | ₹5600 | 2022-05-26 | Buy |
2-PHENYLPROPIONIC ACID Chemical Properties,Uses,Production
Chemical Properties
clear pale yellow to yellow liquid
Uses
2-Phenylpropionic acid is used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.
Definition
ChEBI: A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon.
Synthesis
2-Phenylpropionic acid is prepared:
1) from Benzyl cyanide by Metbylation with
Methyl iodide and Sodamide to produce alpha-Phenylpropionitrile, from which the
acid is produced by acid hydrolysis.
2) from Acetophenone cyanhydrin with Hydriodic
acid.
Purification Methods
Fractionally distil the acid, or recrystallise it from pet ether (b 40-60o) with strong cooling (see references below). [Beilstein 9 II 348.]
2-PHENYLPROPIONIC ACID Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Anlon Healthcare Pvt Ltd | +91-2812562538 +91-7069690081 | Gujarat, India | 54 | 58 | Inquiry |
Venkata Narayana Active Ingredients Pvt Ltd | +91-9940284484 +91-9840119000 | Tamil Nadu, India | 22 | 58 | Inquiry |
Anlon Healthcare Pvt., Ltd. | 91-281-2562538 | Gujarat, India | 18 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Kotaru Laboratories Private Limited | 91--9849999231 | Hyderabad, India | 22 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Gitanjali Chemicals Private Limited | 08048361297Ext 878 | Maharashtra, India | 12 | 58 | Inquiry |