5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine
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- ₹7800 - ₹41713.8
- Product name: 5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine
- CAS: 870483-87-7
- MF: C20H22N4O3
- MW: 366.41
- EINECS:
- MDL Number:MFCD12024701
- Synonyms:5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine;GW2580;SC-203877;SC-203877/GW2580;2,4-Pyrimidinediamine, 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-;5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-Pyrimidinediamine;5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine;GW2580, >=98%
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 25MG
- 50MG
- 250MG
- ManufacturerTCI Chemicals (India)
- Product numberG0504
- Product descriptionGW 2580
- Packaging50MG
- Price₹7800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberG0504
- Product descriptionGW 2580
- Packaging250MG
- Price₹20300
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1047
- Product descriptionGW2580 ≥98% (HPLC)
- Packaging5MG
- Price₹10334.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number344036-M
- Product descriptioncFMS Receptor Tyrosine Kinase Inhibitor - CAS 870483-87-7 - Calbiochem The cFMS Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 870483-87-7, controls the biological activity of cFMS. This small molecule/inhi
- Packaging1MG
- Price₹11880.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1047
- Product descriptionGW2580 ≥98% (HPLC)
- Packaging25MG
- Price₹41713.8
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | G0504 | GW 2580 | 50MG | ₹7800 | 2022-05-26 | Buy |
TCI Chemicals (India) | G0504 | GW 2580 | 250MG | ₹20300 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML1047 | GW2580 ≥98% (HPLC) | 5MG | ₹10334.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 344036-M | cFMS Receptor Tyrosine Kinase Inhibitor - CAS 870483-87-7 - Calbiochem The cFMS Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 870483-87-7, controls the biological activity of cFMS. This small molecule/inhi | 1MG | ₹11880.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1047 | GW2580 ≥98% (HPLC) | 25MG | ₹41713.8 | 2022-06-14 | Buy |
Properties
Boiling point :617.5±65.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
pka :7.11±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
pka :7.11±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
Symbol(GHS): |
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Description
cFMS kinase is the cellular homolog of the v-FMS oncogene product of the Susan McDonough strain of the feline sarcoma virus. It can autophosphorlyate colony-stimulating factor (CSF-1), which promotes the survival, proliferation, and differentiation of mononuclear phagocytes. GW 2580 selectively inhibits cFMS kinase (IC50 = 0.03 μM), preventing CSF-1-induced monocyte growth with an IC50 value of 0.14 μM. At 75-100 mg/kg, it has been shown to inhibit joint connective tissue and bone degradation in mouse models of arthritis.Related product price
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