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Chidamide

Chidamide Structure
  • ₹0
  • Product name: Chidamide
  • CAS: 743420-02-2
  • MF: C22H19FN4O2
  • MW: 390.41
  • EINECS:
  • MDL Number:
  • Synonyms:(E)-N-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide Chidamide;Chidamide;(E)-N-(2-aMino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylaMido)Methyl)benzaMide;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]benzamide;De-4-fluoro 5-Fluoro Chidamide;CHIDAMIDE;(E)-N-(2-AMINO-5-FLUOROPHENYL)-4-((3-(PYRIDIN-3-YL)ACRYLAMIDO)METHYL)BENZAMIDE;(E)-N-(2-AMINO-5-FLUOROPHENYL)-4-((3-(PYRIDIN-3-YL)ACRYLAMIDO)METHYL)BENZAMIDE CHIDAMIDE;N-(2-AMINO-5-FLUOROPHENYL)-4-[[[1-OXO-3-(3-PYRIDINYL)-2-PROPENYL]AMINO]METHYL;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl;Chidamide D4
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>145°C (dec.)
Boiling point :600.2±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :12.30±0.70(Predicted)
color :Off-White to Pale Beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Chidamide is a histone deacetylase inhibitor that increases histone H3 acetylation levels in LoVo and HT-29 colon cancer cells at concentrations as low as 4 μM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. Furthermore, chidamide treatment dose-dependently upregulates p21 protein expression, downregulates Cdk4, and induces cell cycle arrest at the G0/G1 phase.

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Related product price

Suppliers and manufacturers

career henan chemical co
Chidamide
₹1.00 /1KG
Chidamide CAS:743420-02-2
Dideu Industries Group Limited
Chidamide USP/EP/BP
₹1.10 /1g
Chidamide USP/EP/BP CAS:743420-02-2
CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Win-Win chemical CO., Limited
InvivoChem
Coresyn Pharmatech Co., Ltd.
Nantong HI-FUTURE Biology Co., Ltd.
ShenZhen Trendseen Biological Technology Co.,Ltd.