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ChemicalBook > Product Catalogue >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >Dabigatran

Dabigatran

Dabigatran Structure
  • ₹0
  • Product name: Dabigatran
  • CAS: 211914-51-1
  • MF: C25H25N7O3
  • MW: 471.51
  • EINECS:
  • MDL Number:MFCD09837830
  • Synonyms:3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met;BIBR 953(Dabigatran);N-[[2-[[[4-(AMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benzo[d]iMidazol-5-yl]carbonyl]-N-pyridin-2-yl-beta-alanine;N-[(2-{[(4-carbaMiMidoylphenyl)aMino]Methyl}-1-Methyl-1HbenziMidazol- 5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine;BIBR 953 (Dabigatran, Pradaxa);3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Methyl-benzoiMidazole-5-carbonyl]-pyridin-2-yl-aMino];BIB-953;BIBR 953ZW
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :268-272°C
Boiling point :797.1±70.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Aqueous Acid
form :Solid
pka :4.17±0.10(Predicted)
color :White to Brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dabigatran is a potent thrombin inhibitor (Ki = 4.5 nM). It also inhibits trypsin (Ki = 50.3 nM), but only weakly inhibits other serine proteases. Dabigatran has poor bioavailability after oral administration. However, dabigatran etexilate is a double prodrug that has excellent oral bioavailability and undergoes in vivo hydrolytic cleavage to produce dabigatran.

More related product prices

Dabigatran etexilate Rivaroxaban Apixaban 1268524-70-4 Y27632 (hydrochloride) Bortezomib N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride HEXYL CHLOROFORMATE 212322-56-0 2498-50-2 Chloroacetic anhydride 42288-26-6 BI 2536

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Suppliers and manufacturers

GLR Innovations Jigs Chemical ltd SURYA LIFE SCIENCES LIMITED ANWITA APIS J S LABS Lofty labs Glenmark Pharmaceuticals Limited Honour Lab Limited Rivashaa Agrotech Biopharma Pvt. Ltd. Ralington Pharma