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ML281

ML281 Structure
  • ₹0
  • Product name: ML281
  • CAS: 1404437-62-2
  • MF: C22H19N3O2S
  • MW: 389.47
  • EINECS:
  • MDL Number:MFCD25976601
  • Synonyms:ML281;N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide;CS-2166;ML 281;ML-281;N-(4-isopropyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)thiophene-2-carboxamide;2-Thiophenecarboxamide, N-[2-(3,4-dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-;ML281,Inhibitor,ML-281,ML 281,inhibit
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :2-8°C(protect from light)
solubility :DMF: 33 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML 281 is a potent and selective quinoxalinone-based inhibitor of STK33 effectively targeting KRAS-dependent cancers.

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