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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Antimetabolites, Antineoplastic >Carmofur

Carmofur

Carmofur Structure
  • ₹9601.78 - ₹38829.28
  • Product name: Carmofur
  • CAS: 61422-45-5
  • MF: C11H16FN3O3
  • MW: 257.26
  • EINECS:689-431-9
  • MDL Number:MFCD00866284
  • Synonyms:2,4-dioxo-5-fluoro-n-hexyl-1,2,3,4-tetrahydro-1-pyrimidinecarboxamide ;2,4-dioxo-5-fluoro-n-hexyl-3,4-dihydro-1(2h)-pyrimidinecarboxamidme ;3,4-dihydro-2,4-dioxo-5-fluoro-n-hexyl-1(2h)-pyrimidinecarboxamid ;hcfu ;5-FLUORO-1-HEXYLCARBAMOYLURACIL;CARMOFUR;HCFUTM;1-(N-HEXYLCARBAMOYL)-5-FLUOROURACIL
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberC2663
  • Product descriptionCarmofur
  • Packaging5G
  • Price₹14200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1494
  • Product descriptionCarmofur ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹9601.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1494
  • Product descriptionCarmofur ≥98% (HPLC), powder
  • Packaging50MG
  • Price₹38829.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2663 Carmofur 5G ₹14200 2022-05-26 Buy
Sigma-Aldrich(India) C1494 Carmofur ≥98% (HPLC), powder 10MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) C1494 Carmofur ≥98% (HPLC), powder 50MG ₹38829.28 2022-06-14 Buy

Properties

Melting point :110-111
Density :1.2287 (estimate)
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
form :powder
pka :6.94±0.10(Predicted)
color :white to off-white
Merck :14,1844
CAS DataBase Reference :61422-45-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.

Description

Carmofur is a fluorinated pyrimidine and derivative of fluorouracil . It has anti-neoplastic activity and is commonly used as adjuvant therapy following resection for some forms of cancer. Recent studies have shown that carmofur is a potent inhibitor of acid ceramidase (IC50 = 29 nM), an enzyme that is over-expressed in some tumors.

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