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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >Adrenergic Receptor agonists >Mirabegron

Mirabegron

Mirabegron Structure
  • ₹10673.45 - ₹42975.25
  • Product name: Mirabegron
  • CAS: 223673-61-8
  • MF: C21H24N4O2S
  • MW: 396.51
  • EINECS:800-126-3
  • MDL Number:MFCD11100356
  • Synonyms:2-AMino-N-[4-[2-[[(2R)-2-hydroxy-2-phenyl-ethyl]aMino]-ethyl]phenyl]-4-thiazoleacetaMide;2-(2-aMino-1,3-thiazol-4-yl)-N-(4-{2-[(2-hydroxy-2-phenylethyl)aMino]ethyl}phenyl)acetaMide;(2R)-2-(2-AMinothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)aMino]ethyl]acetic Acid Anilide;4-Thiazoleacetamide, 2-amino-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)-;Mirabegron;N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide;YM 178;Mirabegron(YM 178)
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2480
  • Product descriptionMirabegron ≥98% (HPLC)
  • Packaging5MG
  • Price₹10673.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2480
  • Product descriptionMirabegron ≥98% (HPLC)
  • Packaging25MG
  • Price₹42975.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML2480 Mirabegron ≥98% (HPLC) 5MG ₹10673.45 2022-06-14 Buy
Sigma-Aldrich(India) SML2480 Mirabegron ≥98% (HPLC) 25MG ₹42975.25 2022-06-14 Buy

Properties

Melting point :138-140°C
Boiling point :690.0±55.0 °C(Predicted)
Density :1.313
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Chloroform (Slightly, Heated), Methanol (Slightly)
form :Solid
pka :13.51±0.70(Predicted)
color :White to Pale Yellow
InChIKey :PBAPPPCECJKMCM-IBGZPJMESA-N
SMILES :S1C=C(CC(NC2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2)=O)N=C1N
CAS DataBase Reference :223673-61-8

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Mirabegron is a β3-adrenergic receptor agonist (EC50 = 22.4 nM) that displays potent selectivity for β3 compared to the β1 and β2 receptor subtypes (EC50s ≥ 10 μM). It has been shown to relax rat and human bladder strips precontracted with carbamoylcholine with EC50 values of 5.1 and 0.78 μM, respectively. Clinical trials have supported the efficacy of mirabegron in overactive bladder therapy.

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Suppliers and manufacturers

Jigs Chemical ltd HEMA PHARMACEUTICALS PVT LTD AVD pharmaceuticals Pvt Ltd Indian Drugs And Chemicals Dr. Reddy's Laboratories Ltd Global Pharma SNA HEALTHCARE PVT LTD GLP Pharma Standards Lewens Labs Metrochem API Private Limited