NS 1619
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- ₹12230 - ₹49340
- Product name: NS 1619
- CAS: 153587-01-0
- MF: C15H8F6N2O2
- MW: 362.23
- EINECS:
- MDL Number:MFCD00928190
- Synonyms:NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;NS1619;NS 1619;NS 161;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberN170
- Product descriptionNS 1619 powder
- Packaging25MG
- Price₹49340
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN170
- Product descriptionNS 1619 powder
- Packaging5MG
- Price₹12230
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N170 | NS 1619 powder | 25MG | ₹49340 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N170 | NS 1619 powder | 5MG | ₹12230 | 2022-06-14 | Buy |
Properties
Density :1.563±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka :8.32±0.48(Predicted)
form :solid
color :white
Water Solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47mg/mL
ethanol: 26.6mg/mL
0.1 M NaOH: 5.2mg/mL
DMSO: 5.3mg/mL
H2O: insoluble
storage temp. :Inert atmosphere,2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka :8.32±0.48(Predicted)
form :solid
color :white
Water Solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47mg/mL
ethanol: 26.6mg/mL
0.1 M NaOH: 5.2mg/mL
DMSO: 5.3mg/mL
H2O: insoluble
Safety Information
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Description
NS 1619 is a calcium-dependent activator of large-conductance Ca2+-activated K+ (BKCa) channels in vascular smooth muscle. It is typically used at a concentration of 30 μM to hyperpolarize the membrane potential of single myocytes during studies of smooth muscle relaxation and vasodilation. Studies suggest that activation of BKCa channels by NS 1619 can protect the cardiac muscle against pulmonary hypertension as well as ischemia and reperfusion injury in various animal models.Related product price
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