STF-62247
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- ₹11730 - ₹15923.58
- Product name: STF-62247
- CAS: 315702-99-9
- MF: C15H13N3S
- MW: 267.35
- EINECS:631-141-1
- MDL Number:MFCD01121974
- Synonyms:STF-62247;N-(3-Methylphenyl)-4-(4-pyridinyl)-1,3-thiazol-2-amine;N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolaMine;4-(pyridin-4-yl)-N-m-tolylthiazol-2-amine;Autophagy Inducer, STF-62247;STF-62247;STF62247;STF 62247;N-(3-methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine;ERROR
3 prices
Selected condition：
Brand
- Sigma-Aldrich
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- ManufacturerSigma-Aldrich
- Product number189497
- Product descriptionAutophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells both in vitro and in mice in vivo.
- Packaging10MG
- Price₹11730
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number189497
- Product descriptionAutophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells b
- Packaging10MG
- Price₹11730
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS7448
- Product descriptionSTF-62247 ≥98% (HPLC), solid
- Packaging5MG
- Price₹15923.58
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | 189497 | Autophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells both in vitro and in mice in vivo. | 10MG | ₹11730 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 189497 | Autophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells b | 10MG | ₹11730 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S7448 | STF-62247 ≥98% (HPLC), solid | 5MG | ₹15923.58 | 2022-06-14 | Buy |
Properties
Melting point :158-160℃
Density :1.255
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: soluble26mg/mL
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.255
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: soluble26mg/mL
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM). It significantly reduces the growth rate of tumors formed from VHL-deficient cells in mice. STF-62247 induces cytotoxicity in VHL-positive RCC cells only at higher concentrations (IC50 = 16 μM).More related product prices
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