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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Metabolism >PPAR activators >WY-14643

WY-14643

WY-14643 Structure
  • ₹6137.78 - ₹18640.65
  • Product name: WY-14643
  • CAS: 50892-23-4
  • MF: C14H14ClN3O2S
  • MW: 323.8
  • EINECS:
  • MDL Number:MFCD00191335
  • Synonyms:WY-14643/WY14643;((4-chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)-aceticaci ;((4-chloro-6-(2,3-xylidino)-2-pyrimidinyl)thio)-aceticaci ;4-chloro-6-(2,3-xylidino)-2-*pyrimidinylthioaceti ;pirnixicacid ;NSC 310038;Acetic acid, 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-;wyeth14,643
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberC1323
  • Product description[4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic Acid
  • Packaging1G
  • Price₹7400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC1323
  • Product description[4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic Acid
  • Packaging5G
  • Price₹18200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC7081
  • Product descriptionWY-14643
  • Packaging10MG
  • Price₹6137.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC7081
  • Product descriptionWY-14643
  • Packaging50MG
  • Price₹18640.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C1323 [4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic Acid 1G ₹7400 2022-05-26 Buy
TCI Chemicals (India) C1323 [4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic Acid 5G ₹18200 2022-05-26 Buy
Sigma-Aldrich(India) C7081 WY-14643 10MG ₹6137.78 2022-06-14 Buy
Sigma-Aldrich(India) C7081 WY-14643 50MG ₹18640.65 2022-06-14 Buy

Properties

Melting point :155°C
Boiling point :514.4±50.0 °C(Predicted)
Density :1.2984 (rough estimate)
refractive index :1.5630 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 40 mg/ml).
form :White crystalline solid
pka :2.99±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Wy 14643 is a peroxisome proliferator-activated receptor (PPAR activator). Although this compound is primarily an activator of PPARα, it activates PPARγ as well. Activation of PPARδ by Wy 14643 is also observed, but this finding is rare. The potency of Wy 14643 as an activator of PPARα is species dependent, with receptor activation occurring at concentrations as low as 0.1 μM in the mouse compared to 10 μM in Xenopus.

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