Etretinate

- CAS No.
- 54350-48-0
- Chemical Name:
- Etretinate
- Synonyms
- TIGASON;Tegison;Tigasone;Retinoid;ro10-9359;ETRETINATE;Etretinato;tetraenoate;ethyletrinoate;all-trans-ethylester
- CBNumber:
- CB6214647
- Molecular Formula:
- C23H30O3
- Molecular Weight:
- 354.48
- MOL File:
- 54350-48-0.mol
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 104-1050C |
---|---|
Boiling point | 447.69°C (rough estimate) |
Density | 1.0304 (rough estimate) |
refractive index | 1.5480 (estimate) |
storage temp. | Sealed in dry,2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated), Ethyl Acetate (Slightly) |
form | Solid |
color | Light Yellow to Yellow |
Stability | Light Sensitive |
CAS DataBase Reference | 54350-48-0(CAS DataBase Reference) |
EPA Substance Registry System | Etretinate (54350-48-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS07,GHS08,GHS09 |
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Signal word | Danger | |||||||||
Hazard statements | H315-H335-H360D-H410 | |||||||||
Precautionary statements | P201-P202-P261-P273-P302+P352-P308+P313 | |||||||||
HS Code | 2918992090 | |||||||||
Hazardous Substances Data | 54350-48-0(Hazardous Substances Data) | |||||||||
Toxicity | LD50 in mice (1 day): >4000 mg/kg i.p. (Bollag); LD50 (20 day) in mice, rats (mg/kg): 1176, >2000 i.p.; >2000, >4000 orally (Kamm) | |||||||||
NFPA 704 |
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Etretinate price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR2919 | Acitretin Related Compound B pharmaceutical secondary standard, certified reference material | 54350-48-0 | 100MG | ₹61843.23 | 2022-06-14 | Buy |
TCI Chemicals (India) | E1293 | Etretinate | 54350-48-0 | 50MG | ₹4900 | 2022-05-26 | Buy |
TCI Chemicals (India) | E1293 | Etretinate | 54350-48-0 | 250MG | ₹13400 | 2022-05-26 | Buy |
Etretinate Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
World Health Organization (WHO)
Etretinate, a retinol derivative, was introduced in 1981 for the treatment of psoriasis. Its use in pregnant women has resulted in major foetal abnormalities. The manufacturer's information emphasizes that the drug is teratogenic and must not be given to women who are pregnant, and that contraceptive measures must be maintained for at least two years after discontinuation of treatment. In some countries, blood banks are advised not to accept as donors persons who have taken etretinate within the previous year.
Etretinate Preparation Products And Raw materials
Raw materials
Iodoethane
3-Formyl crotonic acid butyl ester
Potassium carbonate
Potassium hydroxide
Sodium hydride
Triphenylphosphine hydrobromide
2-Butenoic acid, 4-hydroxy-3-methyl-, ethyl ester, (2E)-
13-cis-Etretinate
(2E,4E)-5-(4-methoxy-2,3,6-trimethylphenyl)-3-methylpenta-2,4-dien-1-ol
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Global( 160)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
Omcham Labs | 08048372728Ext 857 | Gujarat, India | 90 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6754 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21628 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17365 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
54350-48-0(Etretinate)Related Search:
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2,4,6,8-nonanetetraenoicacid,9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl
3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonanetetraenoicaci
all-trans-ethylester
(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonanetetraenoic acid ethyl ester
(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ethyl
(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ethyl ester
Acitretin Related Compound B (20 mg) (ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate)
Acitretin Related CoMpound B
ethylall-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nona
ethyletrinoate
ro10-9359
tetraenoate
TIGASON
Tegison
(all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid Ethyl Ester
Tigasone
TRIMETHYLMETHOXYPHENYLETHYLRETINOATE
ethyl all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
ETRETINATE
Acitretin ethyl ester
AcitretinEthylEster(ForAcitretin)
(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid ethyl ester
(ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate)
Etretinato
Retinoid
(2E,4E,6E,8E)-Ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester, (2E,4E,6E,8E)-
all-trans-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid Ethyl Ester
Etretinate USP/EP/BP
Etretinate (Ro 10-9359)
Acitretin EP Impurity B
Acitretin Ethyl EsterQ: What is
Acitretin Ethyl Ester Q: What is the CAS Number of
Acitretin Ethyl Ester Q: What is the storage condition of
Acitretin Ethyl Ester Q: What are the applications of
Acitretin Ethyl Ester
Acitretin Related Compound B (ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2, (1011029)
Acitretin Acid Impurity B
Acitretin USP Related Compound B
Acitretin Impurity 7 (Acitretin EP Impurity B)
Avermectin impurity 5
Etretinate, 10 mM in DMSO
Acitretin EP Impurity B (Etretinate, Acitretin USP Related Compound B)
54350-48-0
C23H30O3
Aromatics Compounds
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals
API
Retinoids