4-Amino-1-butanol
- CAS No.
- 13325-10-5
- Chemical Name:
- 4-Amino-1-butanol
- Synonyms
- 4-aminobutan-1-ol;BUTANOLAMINE;4-AMINOBUTANOL;SKL271;N-ABU(4)-OL;H-ABUT(4)-OL;NH2-(CH2)4-OH;4-Aminobutanol-1;2-AcetyLhiophene;4-AMINO-1-BUTANOL
- CBNumber:
- CB7853047
- Molecular Formula:
- C4H11NO
- Molecular Weight:
- 89.14
- MOL File:
- 13325-10-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/7 19:09:42
| Melting point | 16-18 °C (lit.) |
|---|---|
| Boiling point | 206 °C (lit.) |
| Density | 0.967 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 226 °F |
| storage temp. | Store below +30°C. |
| solubility | Acetonitrile (Slightly), Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| pka | 15.10±0.10(Predicted) |
| color | Clear colorless to slightly yellow |
| Water Solubility | MISCIBLE |
| Sensitive | Air Sensitive & Hygroscopic |
| BRN | 1731411 |
| Stability | Unstable in Aqueous Solution |
| CAS DataBase Reference | 13325-10-5(CAS DataBase Reference) |
| NIST Chemistry Reference | NH2(CH2)4OH(13325-10-5) |
| EPA Substance Registry System | 1-Butanol, 4-amino- (13325-10-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-22 | |||||||||
| Safety Statements | 26-36/37/39-45-25 | |||||||||
| RIDADR | UN 2735 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 34 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29221980 | |||||||||
| NFPA 704 |
|
4-Amino-1-butanol price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 178330 | 4-Amino-1-butanol 98% | 13325-10-5 | 1G | ₹2403.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 178330 | 4-Amino-1-butanol 98% | 13325-10-5 | 1G | ₹2403.15 | 2022-06-14 | Buy |
| Sigma-Aldrich | 178330 | 4-Amino-1-butanol 98% | 13325-10-5 | 5G | ₹8010.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 178330 | 4-Amino-1-butanol 98% | 13325-10-5 | 5G | ₹8010.5 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A1013 | 4-Amino-1-butanol min. 98.0 % | 13325-10-5 | 5G | ₹5800 | 2022-05-26 | Buy |
4-Amino-1-butanol Chemical Properties,Uses,Production
Description
4-Amino-1-butanol (4AB) is an important pharmaceutical intermediate compound and a precursor of biodegradable polymers for gene delivery. It can be used in organic synthesis and biological properties studies, among others. In addition, 4-Amino-1-butanol (4AB) has been shown to have a higher CO2 solubility than 2-amino-1-ethanol (MEA), which is potentially useful in solving problems related to flue gas purification[1-2].
Chemical Properties
Very light clear yellow liquid
Uses
4-Amino-1-butanol is a useful intermediate in a variety of organic synthesis. It is mainly used in personal-care products, preparation of water soluble cationic flocculants and ion exchange resins as well as in the preparation of beta-lactam antibiotics. It is used for the production of efficient anionic emulsifiers, nonionic polyethylene emulsions, water treatment, metal treatment and absorption of carbon dioxide gas. It is used as a pigment dispersion aid and curing agent in selected textile -resins.
Preparation
4-Amino-1-butanol (4AB) can be prepared by microbiological methods. we report for the first time the fermentative production of 4AB from glucose by metabolically engineered Corynebacterium glutamicum harboring a newly designed pathway comprising a putrescine (PUT) aminotransferase (encoded by ygjG) and an aldehyde dehydrogenase (encoded by yqhD) from Escherichia coli, which convert PUT to 4AB. Application of several metabolic engineering strategies such as fine-tuning the expression levels of ygjG and yqhD, eliminating competing pathways, and optimizing culture condition further improved 4AB production. Fed-batch culture of the final metabolically engineered C. glutamicum strain produced 24.7?g/L of 4AB[1].
References
[1] CINDY PRICILIA SURYA PRABOWO. Microbial production of 4-amino-1-butanol, a four-carbon amino alcohol[J]. Biotechnology and Bioengineering, 2020. DOI:10.1002/bit.27438.
[2] ZULKIFLI IDRIS . Equilibrium solubility of carbon dioxide in aqueous solutions of 3-amino-1-propanol, 4-amino-1-butanol and 5-amino-1-pentanol at low partial pressures[J]. Fluid Phase Equilibria, 2015. DOI:10.1016/j.fluid.2014.11.028.
4-Amino-1-butanol Preparation Products And Raw materials
Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Allchem Lifescience Pvt. Ltd | +919867655500 | Gujarat, India | 971 | 58 | Inquiry |
| REDDY N REDDY PHARMACEUTICALS | +91-9848096759 +91-9848096759 | Hyderabad, India | 1989 | 58 | Inquiry |
| aSai Vishwa Speciality Chemicals Pvt Ltd | +91-2241276501 +91-9920410867 | Maharashtra, India | 58 | 58 | Inquiry |
| ALLCHEM LIFESCIENCE PVT. LTD | +91 957 472 2211 | New Delhi, India | 322 | 58 | Inquiry |
| aSai Vishwa Speciality Chemicals Pvt. Ltd. | 91-22-41276501 | Maharashtra, India | 27 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| A. B. Enterprises | +91-8048077585 | Mumbai, India | 1396 | 58 | Inquiry |
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