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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Structure
  • ₹9277.03
  • Product name: 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
  • CAS: 284028-90-6
  • MF: C8H10N2OS
  • MW: 182.24
  • EINECS:200-589-5
  • MDL Number:MFCD08703132
  • Synonyms:1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE;DR 2313;7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one;3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one;4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2;4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL-;SC-202756;2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0397
  • Product descriptionDR2313 ≥98% (HPLC)
  • Packaging5MG
  • Price₹9277.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0397 DR2313 ≥98% (HPLC) 5MG ₹9277.03 2022-06-14 Buy

Properties

Boiling point :349.3±52.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :H2O: >2mg/mL (warmed)
pka :1.54±0.20(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PARP Inhibitor XI, DR2313 is a water soluble pyrimidinone compound that functions as a PARP (Poly(ADP-ribose) polymerase) inhibitor. PARP (Poly(ADP-ribose) polymerase) function by triggering DNA repair mechanisms and activating apoptosis in damaged cells. Studies show that DR2313 competes with NAD+ but does not display selectivity among PARP-1 and PARP-2. In addition, in vitro studies of cerebral ischemia exhibiting an overactivation of PARP show that ischemic damage can be reduced by introducing DR2313.

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Suppliers and manufacturers

career henan chemical co
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
₹1.00 /1KG
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE CAS:284028-90-6
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CONIER CHEM AND PHARMA LIMITED
SIMAGCHEM CORP
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Amadis Chemical Company Limited Shanghai Ziqi Biological Technology Co., Ltd. Xiamen Research Biotechnology Co., Ltd.