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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >DNA damage >PARP inhibitors >PJ-34

PJ-34

PJ-34 Structure
  • ₹9490 - ₹27571.28
  • Product name: PJ-34
  • CAS: 344458-15-7
  • MF: C17H17N3O2HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD28142667
  • Synonyms:PJ 34 Hydrochloride;N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamidehydrochloride;PARP Inhibitor VIII, PJ34;PJ-34 hydrate hydrochloride;AcetaMide, N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(diMethylaMino)-, hydrochloride;N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-(diMethylaMino)acetaMide;N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-2-(N,N-dimethylamino)acetamide hydrochloride;N,N-diMethyl-2-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetaMide hydrochloride
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number528150
  • Product descriptionPARP Inhibitor VIII, PJ34 - CAS 344458-15-7 - Calbiochem The PARP Inhibitor VIII, PJ34, also referenced under CAS 344458-15-7, controls the biological activity of PARP. This small molecule/inhibitor is prima
  • Packaging1MG
  • Price₹9490
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number528150
  • Product descriptionPARP Inhibitor VIII, PJ34 - CAS 344458-15-7 - Calbiochem The PARP Inhibitor VIII, PJ34, also referenced under CAS 344458-15-7, controls the biological activity of PARP. This small molecule/inhibitor is prima
  • Packaging5MG
  • Price₹25060.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4365
  • Product descriptionPJ-34 hydrochloride hydrate ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹27571.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 528150 PARP Inhibitor VIII, PJ34 - CAS 344458-15-7 - Calbiochem The PARP Inhibitor VIII, PJ34, also referenced under CAS 344458-15-7, controls the biological activity of PARP. This small molecule/inhibitor is prima 1MG ₹9490 2022-06-14 Buy
Sigma-Aldrich(India) 528150 PARP Inhibitor VIII, PJ34 - CAS 344458-15-7 - Calbiochem The PARP Inhibitor VIII, PJ34, also referenced under CAS 344458-15-7, controls the biological activity of PARP. This small molecule/inhibitor is prima 5MG ₹25060.01 2022-06-14 Buy
Sigma-Aldrich(India) P4365 PJ-34 hydrochloride hydrate ≥98% (HPLC), powder 5MG ₹27571.28 2022-06-14 Buy

Properties

storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: soluble22mg/mL
form :White solid
color :white to yellow
Sensitive :Light Sensitive & Hygroscopic
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. PJ-34 is an inhibitor of PARPs which can be used in cells or in animals. It binds and inhibits the PARP tankyrase1 (IC50 = 1 μM). PJ-34 also inhibits matrix metalloproteinase-2 when used at higher concentrations (IC50 = 56 μM).

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