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ZLN005

ZLN005 Structure
  • ₹7144.5 - ₹28956.88
  • Product name: ZLN005
  • CAS: 49671-76-3
  • MF: C17H18N2
  • MW: 250.34
  • EINECS:
  • MDL Number:MFCD01560221
  • Synonyms:2-(4-TERT-BUTYLPHENYL)-1H-BENZO[D]IMIDAZOLE;2-(4-tert-Butylphenyl)-1H-benzimidazole;2-(4-tert-Butylphenyl)benzimidazole;ZLN005, >=98%;2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole;2-(4-tert-Butylphenyl)benzimidazole ZLN005;ZLN005 2-(4-tert-Butylphenyl)benzimidazole;ZLN005
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0802
  • Product descriptionZLN005 ≥95% (HPLC)
  • Packaging10MG
  • Price₹7144.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0802
  • Product descriptionZLN005 ≥95% (HPLC)
  • Packaging50MG
  • Price₹28956.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0802 ZLN005 ≥95% (HPLC) 10MG ₹7144.5 2022-06-14 Buy
Sigma-Aldrich(India) SML0802 ZLN005 ≥95% (HPLC) 50MG ₹28956.88 2022-06-14 Buy

Properties

Melting point :257-258℃
Boiling point :415.3±38.0 °C(Predicted)
Density :1.102±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble10mg/mL, clear
pka :11.52±0.10(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. ZLN005 is a small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM. Chronic administration of 15 mg/kg/day ZLN005 to diabetic db/db mice increased PGC-1α and downstream gene transcription in skeletal muscle, increasing fat oxidation and improving glucose tolerance, pyruvate tolerance, and insulin sensitivity.

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