LY 2157299
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- ₹8400.2 - ₹33936.38
- Product name: LY 2157299
- CAS: 700874-72-2
- MF: C22H19N5O
- MW: 369.42
- EINECS:-0
- MDL Number:MFCD12923319
- Synonyms:LY 2157299;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide;6-QuinolinecarboxaMide, 4-[5,6-dihydro-2-(6-Methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-;4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxaMideorLY2157299;GALUNISERTIB;Galunisertib,LY2157299;4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide LY 2157299
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML2851
- Product descriptionGalunisertib ≥98% (HPLC)
- Packaging25MG
- Price₹33936.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2851
- Product descriptionGalunisertib ≥98% (HPLC)
- Packaging5MG
- Price₹8400.2
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML2851 | Galunisertib ≥98% (HPLC) | 25MG | ₹33936.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML2851 | Galunisertib ≥98% (HPLC) | 5MG | ₹8400.2 | 2022-06-14 | Buy |
Properties
Melting point :241-242°C
Boiling point :619.0±55.0 °C(Predicted)
Density :1.40
Flash point :328.162℃
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :15.27±0.30(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
CAS DataBase Reference :700874-72-2
Boiling point :619.0±55.0 °C(Predicted)
Density :1.40
Flash point :328.162℃
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :15.27±0.30(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
CAS DataBase Reference :700874-72-2
Safety Information
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Description
LY2157299 is a small molecule inhibitor of the TGF-β receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-β signaling in chemotherapy-induced expansion of cancer stem-like cells in triple negative breast cancer cell lines and xenografts. LY2157299 has also been shown to inhibit the migration and tumor growth of hepatocellular carcinoma cell lines by disrupting Smad-2 phosphorylation.Related product price
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