Regorafenib
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- ₹6800 - ₹14800
- Product name: Regorafenib
- CAS: 755037-03-7
- MF: C21H15ClF4N4O3
- MW: 482.82
- EINECS:815-051-1
- MDL Number:MFCD16038047
- Synonyms:4-[4-({[4-chioro-3-(trifluoroMethyl)phenyl]carbaMoyl}aMino)-3-fluorophenoxy]-pyridine-2-carboxylic acid MethylaMide;REGORAFENIB BAY 73-4506 BAYER HEALTHCARE (SEE ALSO COLORECTAL, LUNG, STOMACH) PHASE II(REGORAFENIB) PHARMACEUTICALS (888) 842-2937WAYNE, NJ;4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]-3-fluorophenoxy]-N-Methyl-2-pyridinecarboxaMide;4-[4-[N'-(4-Chloro-3-trifluoroMethylphenyl)ureido]-3- fluorophenoxy]pyridine-2-carboxylic Acid MethylaMide;regorafinib;Regafenib;Reggae sorafenib;Regorafenib C3X-1410
2 prices
Selected condition:
Brand
- TCI Chemicals (India)
Package
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberR0142
- Product descriptionRegorafenib
- Packaging25MG
- Price₹6800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberR0142
- Product descriptionRegorafenib
- Packaging100MG
- Price₹14800
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | R0142 | Regorafenib | 25MG | ₹6800 | 2022-05-26 | Buy |
TCI Chemicals (India) | R0142 | Regorafenib | 100MG | ₹14800 | 2022-05-26 | Buy |
Properties
Melting point :206.0 to 210.0 °C
Boiling point :513.4±50.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.04±0.70(Predicted)
form :White powder.
color :Pale Pink to Light Pink
CAS DataBase Reference :755037-03-7
Boiling point :513.4±50.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.04±0.70(Predicted)
form :White powder.
color :Pale Pink to Light Pink
CAS DataBase Reference :755037-03-7
Safety Information
Symbol(GHS): |
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Description
Regorafenib is an orally-bioavailable multi-kinase inhibitor that is structurally related to sorafenib (BAY 43-9006; ), another multi-kinase inhibitor with applications in cancer. Regorafenib inhibits c-Raf, B-Raf, VEGFR1, VEGFR2, VEGFR3, Tie2, PDGFRβ, FGFR1, c-Kit, and RET with IC50 values of 2.5, 28, 13, 4.2, 46, 311, 22, 202, 7, and 1.5 nM, respectively, as well as other kinases. It also inhibits soluble epoxide hydrolase (IC50 = 0.5 nM). Regorafenib has value against a range of cancers, including advanced colorectal cancer.More related product prices
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