Phenobarbital sodium
![Phenobarbital sodium Structure](CAS/GIF/57-30-7.gif)
- CAS No.
- 57-30-7
- Chemical Name:
- Phenobarbital sodium
- Synonyms
- sodiumluminal;LUMINAL SODIUM;gardenalsodium;phenobalsodium;phenobarbitalna;solphenobarbital;solphenobarbitone;LUMINAL SODIUM SALT;fenobarbitalnatrium;phenobarbitalelixir
- CBNumber:
- CB5147742
- Molecular Formula:
- C12H12N2O3.Na
- Molecular Weight:
- 254.22
- MOL File:
- 57-30-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/15 10:43:58
Melting point | 175°C |
---|---|
solubility | H2O: 1 g/mL |
form | Solid |
color | White to Off-White |
PH | pH (100g/l, 25℃) : 9.0~11.0 |
Water Solubility | >=10 g/100 mL at 20 ºC |
Merck | 13,7319 |
BRN | 3802044 |
Stability | Hygroscopic |
CAS DataBase Reference | 57-30-7(CAS DataBase Reference) |
EPA Substance Registry System | Phenobarbital sodium (57-30-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS06,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H301-H317-H351 |
Precautionary statements | P202-P261-P264-P280-P301+P310-P302+P352 |
Hazard Codes | T |
Risk Statements | 25-40-43 |
Safety Statements | 22-36/37/39-45 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | - |
RTECS | CQ7000000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Toxicity | LD50 orally in rats: 660 mg/kg (Schaffarzick, Brown) |
Phenobarbital sodium Chemical Properties,Uses,Production
Chemical Properties
Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y7 (2.2.2, Method II).
Uses
Phenobarbital sodium salt has been used:
- to anesthetize mice for inducing ischemia-reperfusion injury
- as a positive control for the activation of constitutive androstane receptor (CAR)
- in bioluminescent yeast bioreporters (BLYAS) assay
Definition
ChEBI: A barbiturate that is the sodium salt of phenobarbital (barbituric acid substituted at C-5 by ethyl and phenyl groups).
General Description
Odorless white crystalline powder. Aqueous solutions are alkaline to litmus and phenolphthalein (pH approximately 9.3). Bitter taste. A narcotic.
Air & Water Reactions
Hygroscopic. May be sensitive to prolonged exposure to air. Water soluble. Aqueous solutions are unstable, but may be kept at or below 50°F for a few days.
Reactivity Profile
Phenobarbital sodium can react with strong oxidizing agents. Incompatible with ammonium salts and chloral hydrate. Also incompatible with acids and acidic substances .
Fire Hazard
Flash point data for Phenobarbital sodium are not available; however, Phenobarbital sodium is probably combustible.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intravenous, intraperitoneal, intraduodenal, and subcutaneous routes. Human systemic effects by ingestion: nausea or vomiting and coma. Experimental reproductive effects. Mutation data reported. Used to treat epilepsy, as a hypnotic and sedative. When heated to decomposition it emits toxic fumes of NOx and NazO. See also BARBITURATES
Phenobarbital sodium Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Harman Finochem Ltd | +91-2226528080 +91-2226528080 | Maharashtra, India | 37 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
HARMAN FINOCHEM LTD | +91 22 26528080 | New Delhi, India | 29 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Triveni Interchem Private Limited (Group Of Triveni... | 08046042087 | Gujarat, India | 497 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25196 | 58 | Inquiry |
United States Biological | 800.520.3011 or 781.639.5092 | United States | 6256 | 80 | Inquiry |
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