KU-55933
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- ₹9536.83 - ₹38818.45
- Product name: KU-55933
- CAS: 587871-26-9
- MF: C21H17NO3S2
- MW: 395.49
- EINECS:
- MDL Number:MFCD08276985
- Synonyms:2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE;2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one;KU-55933 (ATM Kinase Inhibitor);KU-55933, >99%;KV-55933;2-morpholino-6-(thianthren-1-yl)-4H-pyran-4-one;2-Morpholin-4-yl-6-thianthren-1-ylpyran-4-one KU-55933 (ATM Kinase Inhibitor);KU 55933, >=98%
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1109
- Product descriptionKU-55933 ≥98% (HPLC)
- Packaging5MG
- Price₹9536.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1109
- Product descriptionKU-55933 ≥98% (HPLC)
- Packaging25MG
- Price₹38818.45
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1109 | KU-55933 ≥98% (HPLC) | 5MG | ₹9536.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1109 | KU-55933 ≥98% (HPLC) | 25MG | ₹38818.45 | 2022-06-14 | Buy |
Properties
Boiling point :628.0±55.0 °C(Predicted)
Density :1.419±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml)
pka :0.33±0.20(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Density :1.419±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml)
pka :0.33±0.20(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Safety Information
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Description
Ku-55933 is a potent ATP-competitive inhibitor of the ataxia-telangiectasia mutated (ATM) kinase (IC50 = 13 nM; Ki = 2.2 nM). Inhibition of ATM by Ku-55933 blocks radiation-induced phosphorylation of downstream cellular targets and sensitizes cells to the cytotoxic effects of both ionizing radiation and chemotherapeutic agents. Ku-55933 induces senescent breast, lung, and colon carcinoma cells to undergo cell death. It also inhibits HIV-1 replication in C8166 human T-lymophocyte cells with an IC50 value of 2.4 μM.More related product prices
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