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Aspoxicillin

CAS No.: 63358-49-6

Chemical Name:: Aspoxicillin

Synonyms: ASPC;DOYE;Doyle;TA 058;Aspoxicilin;ASPOXICILLIN;Aspoxicillin (~80%);ASPOXICILLIN 3-HYDRATE;Aspoxicillin USP/EP/BP;N4-Methyl-D-aspariginylamoxicillin

CBNumber:: CB1452855

Molecular Formula:: C21H27N5O7S

Molecular Weight:: 493.53

MOL File:: 63358-49-6.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:01

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Aspoxicillin Properties

Melting point	195-198° (dec)
Boiling point	985.1±65.0 °C(Predicted)
Density	1.51±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly, Sonicated), Methanol (Slightly)
pka	2.44±0.50(Predicted)
form	Solid
color	White to Off-White
Water Solubility	Water : 25 mg/mL (50.66 mM; Need ultrasonic)
Stability	Hygroscopic
CAS DataBase Reference	63358-49-6

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3
RTECS	MB7548000

Aspoxicillin Chemical Properties,Uses,Production

Description

Aspoxicillin is an injectable, amino acid-type penicillin highly active against Gram-positive and Gram-negative bacteria, including the β-lactamase producing Bacillus frugilis. It is reportedly effective in the treatment of peritonitis, pneumonia and bronchitis.

Antimicrobial activity

An acylaminopenicillin, synthesized from amoxicillin. It is more active than carbenicillin against Ps. aeruginosa and is less active than piperacillin against Staph. aureus, H. influenzae, the Enterobacteriaceae and Ps. aeruginosa. It is not absorbed when dosed orally; the plasma half-life is 87 min after intravenous infusion.
Aspoxicillin has been used in the treatment of respiratory, skin and soft tissue and urinary infections in adults and children, and, in combination with aminoglycosides, against gynecological infections and infections in patients with hematological disorders.

Aspoxicillin Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide Amoxicillin 3-Nitrobenzenesulfonyl chloride Thioacetamide Activ Ester

Citric acid Dicyclohexylcarbodiimide 4-Hydroxy-D-(-)-2-phenylglycine Benzyl chloroformate Triethylamine

6-Aminopenicillanic acid PALLADIUM ON STRONTIUM CARBONATE, REDUCED

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Preparation Products

Aspoxicillin Suppliers

Global( 81)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29888	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49392	58	Inquiry
SIMAGCHEM CORP	+86-13806087780	China	17367	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	China	34571	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	China	8744	58	Inquiry
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15395	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
AFINE CHEMICALS LIMITED	58

63358-49-6(Aspoxicillin)Related Search:

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TRIS(2-AMINOETHYL)AMINE D-ASPARTIC ACID ALPHA-AMIDE HYDROCHLORIDE 4-DIISOPROPYLAMINO-1-BUTANOL

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ASPOXICILLIN (2s,5r,6r)-6-[(2r)-2-[(2r)-2-amino-3-(n-methylcarbamoyl)-propionamido]-2-(p-hydroxyphenyl)acetamido]-3,3-dimehtyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate glycinamide,n-methyl-d-asparaginyl-n-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-a n(sup4)-methyl-d-asparagininylamoxicillin zabicyclo(3.2.0)hept-6-yl)-d-2-(4-hydroxyphenyl)-,(2s-(2-alpha,5-alpha,6-beta) Aspoxicilin Doyle Glycinamide, N-methyl-D-asparaginyl-N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-D-2-(4-hydroxyphenyl)-, [2S-(2a,5a,6b)]- Glycinamide, N-methyl-D-asparaginyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-(4-hydroxyphenyl)-, (2R)- TA 058 ASPOXICILLIN 3-HYDRATE ASPC DOYE (2S，5R，6R)-6-[(2R)-2-[(2R)-2-Amino-3-(methylearbamoyl)propionamido]-2-(ρ-hydroxyphenyl)acetamido]-3，3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-6α-[[(R)-[[(2R)-2-Amino-4-(methylamino)-1,4-dioxobutyl]amino](4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid 6α-[(R)-2-(4-Hydroxyphenyl)-2-[[(2R)-3-(methylcarbamoyl)-2-aminopropanoyl]amino]acetylamino]penicillanic acid N4-Methyl-D-Asn-4-hydroxy-D-phenyl Gly-N-[(2S,5β)-2β-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6α-yl]-NH2 N4-Methyl-D-aspariginylamoxicillin Aspoxicillin USP/EP/BP Aspoxicillin (~80%) Benzenemethanamine,N-2-propen-6-yl- Aspoxicillin,inhibit,pleuropneumoniae,Inhibitor,penicillin,Actinobacillus,antimicrobial,Bacterial 63358-49-6 91878-06-9 C21H27N5O7S C21H27N5O7S3H2O AR to AZAntibiotics A Alphabetic Chemical Structure Chromatography OthersAnalytical Standards Pharmacology Standards