Indinavir sulfate
- CAS No.
- 157810-81-6
- Chemical Name:
- Indinavir sulfate
- Synonyms
- IDV;MK-639;CS-535;CS-1357;CRIXIVAN;MK-639 sulfate;MK-639,Crixivan;L735524 sulfate;INDINAVIR SULFATE;INDINAVIR SULPHATE
- CBNumber:
- CB9123498
- Molecular Formula:
- C36H49N5O8S
- Molecular Weight:
- 711.87
- MOL File:
- 157810-81-6.mol
- Modify Date:
- 2023/9/4 16:42:00
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
NFPA 704 |
|
Indinavir sulfate Chemical Properties,Uses,Production
Description
Indinavir is an HIV-1 protease inhibitor (Ki = 0.358 nM). It is selective for HIV-1 protease over HIV-2 protease (Ki = 3.316 nM), as well as human cathepsin D, porcine pepsin, bovine chymosin, human plasma renin, Factor Xa, and elastase at 10 μM. It is also selective for wild-type HIV-1 protease over the protease inhibitor-resistant mutants A-44, K-60, and V-18 (Kis = 0.24, 15, 50, and 40 nM, respectively). Indinavir is active against multiple HIV-1 variants in cell-based assays (IC95s = 12-100 nM). Formulations containing indinavir have been used in combination with antiretroviral agents in the treatment of HIV infection.
Chemical Properties
Crystalline Solid
Uses
Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product.
Hazard
Moderately toxic by ingestion.
Indinavir sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
Clinse Labs Private Limited. | +091-40-23778611 | New Delhi, India | 372 | 30 | Inquiry |
Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
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