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Indinavir sulfate

Indinavir sulfate Structure
CAS No.
157810-81-6
Chemical Name:
Indinavir sulfate
Synonyms
IDV;MK-639;CS-535;CS-1357;CRIXIVAN;MK-639 sulfate;MK-639,Crixivan;L735524 sulfate;INDINAVIR SULFATE;INDINAVIR SULPHATE
CBNumber:
CB9123498
Molecular Formula:
C36H49N5O8S
Molecular Weight:
711.87
MOL File:
157810-81-6.mol
Modify Date:
2023/9/4 16:42:00

Indinavir sulfate Properties

Melting point 150-153°C (dec)
storage temp. -20°C Freezer
solubility Freely soluble in water, soluble in methanol, practically insoluble in heptane.
form Solid
color White to Off-White
Water Solubility >100g/L(temperature not stated)
BCS Class 2,4

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
NFPA 704
0
2 0

Indinavir sulfate Chemical Properties,Uses,Production

Description

Indinavir is an HIV-1 protease inhibitor (Ki = 0.358 nM). It is selective for HIV-1 protease over HIV-2 protease (Ki = 3.316 nM), as well as human cathepsin D, porcine pepsin, bovine chymosin, human plasma renin, Factor Xa, and elastase at 10 μM. It is also selective for wild-type HIV-1 protease over the protease inhibitor-resistant mutants A-44, K-60, and V-18 (Kis = 0.24, 15, 50, and 40 nM, respectively). Indinavir is active against multiple HIV-1 variants in cell-based assays (IC95s = 12-100 nM). Formulations containing indinavir have been used in combination with antiretroviral agents in the treatment of HIV infection.

Chemical Properties

Crystalline Solid

Uses

Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product.

Hazard

Moderately toxic by ingestion.

Indinavir sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 166)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Hetero Drugs Limited +91-4023704923 +91-4023704923 Telangana, India 296 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
Clinse Labs Private Limited. +091-40-23778611 New Delhi, India 372 30 Inquiry
Medilink Pharmachem +91 (79) 3007-0133 New Delhi, India 424 50 Inquiry
Xiamen AmoyChem Co., Ltd +86-592-6051114 +8618959220845 China 6387 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry

Indinavir sulfate Spectrum

CRIXIVAN INDINAVIR SULFATE INDINAVIR SULPHATE (1(1s,2r),5(s))-2,3,5-trideoxy-n-(2,3-dihydro-2-hydroxy-1h-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-d-erythro-pentonamide sulfate MK-639 indinavirsulfate(subjecttopatentfree) IDV MK-639,Crixivan 2,3,5-Trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide INDIGOWOADROOTEXTRACT Indinavir sulfate###Unii-9mg78X43zt Indinavir sulfate ethanolate Indinavir & Indinavir Sulfate Indinavir sulfate 157810-81-6 N-tert-butyl-1-[2-hydroxy-5-[(2-hydroxy-2,3-dihydro-1H-inden-1-yl)amino]-5-oxo-4-(phenylmethyl)pentyl]-4-(3-pyridinylmethyl)-2-piperazinecarboxamide CS-1357 Indinavir, MK 639, L 735524 CS-535 (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxyindan-1-yl]amino]-5-oxo-pentyl]-N-tert-butyl-4-(3-pyridylmethyl)piperazine-2-carboxamide L735524 sulfate MK-639 sulfate Indinavir sulfate USP/EP/BP (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxyinda... Indinavir sulfateQ: What is Indinavir sulfate Q: What is the CAS Number of Indinavir sulfate Q: What is the storage condition of Indinavir sulfate D-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-, sulfate (1:1) 157810-81-6 C36H47N5O4H2O4S C36H47N5O4 C36H47N5O4H2SO4 C36H49N5O8S Active Pharmaceutical Ingredients Indinavir peptides Other APIs Anti-viral Compounds Anti-virals Inhibitors Intermediates & Fine Chemicals Non-nucleoside Reverse Transcriptase Pharmaceuticals Coronavirus