4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
![4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE Structure](/StructureFile/ChemBookStructure3/GIF/CB3243082.gif)
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- ₹13184.85 - ₹51180.6
- Product name: 4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
- CAS: 170569-86-5
- MF: C16H11ClF3N3O2S
- MW: 401.79
- EINECS:
- MDL Number:MFCD00941297
- Synonyms:SC-236;4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE;4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOL-1-YL]BENZENESULFONAMIDE;SC-58236;Benzenesulfonamide, 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-;SC 236 - SC 58236;SC-236,gastric,PPAR,cancer,ischemia,Liver,inhibit,allodynia,Inhibitor,fibrogenesis,neuroprotection,COX,Cyclooxygenase,Apoptosis,TNF-α,Peroxisome proliferator-activated receptors,fibrosis,SC236
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0106
- Product descriptionSC-236 ≥98% (HPLC)
- Packaging5MG
- Price₹13184.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0106
- Product descriptionSC-236 ≥98% (HPLC)
- Packaging25MG
- Price₹51180.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PZ0106 | SC-236 ≥98% (HPLC) | 5MG | ₹13184.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PZ0106 | SC-236 ≥98% (HPLC) | 25MG | ₹51180.6 | 2022-06-14 | Buy |
Properties
Melting point :146-148°C
Boiling point :543.4±60.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
pka :9.66±0.10(Predicted)
color :white to off-white
Boiling point :543.4±60.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
pka :9.66±0.10(Predicted)
color :white to off-white
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
SC-236 is a highly selective and potent inhibitor of Cox-2 (IC50 of 10 nM) which also inhibits Cox-1 (IC50 of 17.8 μM) and has antitumor properties. SC-236 exhibits longer half-life time and reduced gastric toxicity in the fasting rat model. SC-236 has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. SC-236 exhibits a potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases.More related product prices
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