VX 702
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- ₹5000 - ₹16000
- Product name: VX 702
- CAS: 745833-23-2
- MF: C19H12F4N4O2
- MW: 404.32
- EINECS:
- MDL Number:MFCD11616590
- Synonyms:6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide;VX 702;6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide VX-702;VX 702 6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide;VX702;VX-702;2-(2,4-Difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide;(479543-46-9) vx 702;CS-1840
2 prices
Selected condition：
Brand
- TCI Chemicals (India)
Package
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberV0147
- Product descriptionVX-702
- Packaging25MG
- Price₹5000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberV0147
- Product descriptionVX-702
- Packaging100MG
- Price₹16000
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | V0147 | VX-702 | 25MG | ₹5000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | V0147 | VX-702 | 100MG | ₹16000 | 2022-05-26 | Buy |
Properties
Boiling point :555.2±60.0 °C(Predicted)
Density :1.503
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 2 mg/ml)
form :solid
pka :10.65±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference :745833-23-2
Density :1.503
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 2 mg/ml)
form :solid
pka :10.65±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference :745833-23-2
Safety Information
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Description
VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38α and p38β (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1β, and TNF-α production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml, respectively. VX-702, at 1 μM, inhibits activation of p38 in platelets by thrombin, U-46619 , or collagen but does not block platelet aggregation in response to collagen. Although orally active, VX-702 provides only transient suppression of biomarkers of inflammation in ongoing rheumatoid arthritis.More related product prices
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