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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Apoptosis >TNF-alpha inhibitors >Necrostatin-1

Necrostatin-1

Necrostatin-1 Structure
  • ₹11098 - ₹36393.65
  • Product name: Necrostatin-1
  • CAS: 4311-88-0
  • MF: C13H13N3OS
  • MW: 259.33
  • EINECS:200-256-5
  • MDL Number:MFCD00056916
  • Synonyms:Necrostatin-1, >=98%;IFLAB-BB F0911-6127;5-(INDOL-3-YLMETHYL)-3-METHYL-2-THIO-HYDANTOIN;NECROSTATIN-1;MTH-DL-TRYPTOPHAN;MTH-DL-Tryptophan Methylthiohydantoin-DL-tryptophan;5-(1H-INDOL-3-YLMETHYL)-3-METHYL-2-THIOXO-4-IMIDAZOLIDINONE;5-(1H-Indole-3ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
5 prices
Selected condition:

Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 20mg
  • 25MG
  • 100MG
  • ManufacturerALFA India
  • Product numberALF-J65341-FPL
  • Product descriptionNecrostatin-1
  • Packaging20mg
  • Price₹11098
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberN1174
  • Product descriptionNecrostatin-1
  • Packaging100MG
  • Price₹19800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9037
  • Product descriptionNecrostatin-1 ≥98% (HPLC)
  • Packaging10MG
  • Price₹16562.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number480065
  • Product descriptionNecrostatin-1 - CAS 4311-88-0 - Calbiochem Necrostatin-1, CAS 4311-88-0, is a cell-permeable, potent, and selective blocker of necroptosis (EC?? = 494 nM in FADD-deficient Jurkat cells treated
  • Packaging5MG
  • Price₹17579.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9037
  • Product descriptionNecrostatin-1 ≥98% (HPLC)
  • Packaging25MG
  • Price₹36393.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J65341-FPL Necrostatin-1 20mg ₹11098 2022-05-26 Buy
TCI Chemicals (India) N1174 Necrostatin-1 100MG ₹19800 2022-05-26 Buy
Sigma-Aldrich(India) N9037 Necrostatin-1 ≥98% (HPLC) 10MG ₹16562.25 2022-06-14 Buy
Sigma-Aldrich(India) 480065 Necrostatin-1 - CAS 4311-88-0 - Calbiochem Necrostatin-1, CAS 4311-88-0, is a cell-permeable, potent, and selective blocker of necroptosis (EC?? = 494 nM in FADD-deficient Jurkat cells treated 5MG ₹17579.99 2022-06-14 Buy
Sigma-Aldrich(India) N9037 Necrostatin-1 ≥98% (HPLC) 25MG ₹36393.65 2022-06-14 Buy

Properties

Melting point :151℃
Boiling point :441.9±37.0 °C(Predicted)
Density :1.40±0.1 g/cm3 (20 ºC 760 Torr)
Flash point :93.3℃
storage temp. :-20°C
solubility :DMSO: >10 mg/mL
form :solid
pka :9.46±0.40(Predicted)
color :Pale yellow
Sensitive :Light Sensitive
Stability :Stable for 2 years from date of purchase as supplied.? Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells.

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