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1-Aminocyclopropanecarboxylic acid

1-Aminocyclopropanecarboxylic acid Structure
CAS No.
22059-21-8
Chemical Name:
1-Aminocyclopropanecarboxylic acid
Synonyms
ACC;1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID;1-AMinocyclopropane-1-carboxylate;Ac3c;H-ACPC-OH;AMinocyclopropanecarboxylic acid;Cyclopropanecarboxylic acid, 1-amino-;Acpc-OH;1,1-ACCP;NSC 98430
CBNumber:
CB6401146
Molecular Formula:
C4H7NO2
Molecular Weight:
101.1
MOL File:
22059-21-8.mol
Modify Date:
2024/10/25 16:21:11

1-Aminocyclopropanecarboxylic acid Properties

Melting point 229-231 °C (lit.)
Boiling point 189.47°C (rough estimate)
Density 1.2245 (rough estimate)
refractive index 1.4340 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Water (Slightly)
pka 2.29±0.20(Predicted)
form Powder and Granules
color White to off-white
Water Solubility Soluble in water.
BRN 2076413
Stability Store in freezer at -20°C
InChI InChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
InChIKey PAJPWUMXBYXFCZ-UHFFFAOYSA-N
SMILES C1(N)(C(O)=O)CC1
CAS DataBase Reference 22059-21-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  GZ1110000
Hazard Note  Irritant
HS Code  29213000
NFPA 704
0
2 0

1-Aminocyclopropanecarboxylic acid price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A3903 1-Aminocyclopropanecarboxylic acid ≥98% (TLC) 22059-21-8 100MG ₹9829.1 2022-06-14 Buy
Sigma-Aldrich(India) A3903 1-Aminocyclopropanecarboxylic acid ≥98% (TLC) 22059-21-8 250MG ₹16031.83 2022-06-14 Buy
Sigma-Aldrich(India) A3903 1-Aminocyclopropanecarboxylic acid ≥98% (TLC) 22059-21-8 1G ₹56051.85 2022-06-14 Buy
Sigma-Aldrich(India) 149101-M 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. 22059-21-8 250MG ₹11030 2022-06-14 Buy
Sigma-Aldrich(India) 149101-M 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. 22059-21-8 1G ₹34630 2022-06-14 Buy
Product number Packaging Price Buy
A3903 100MG ₹9829.1 Buy
A3903 250MG ₹16031.83 Buy
A3903 1G ₹56051.85 Buy
149101-M 250MG ₹11030 Buy
149101-M 1G ₹34630 Buy

1-Aminocyclopropanecarboxylic acid Chemical Properties,Uses,Production

Description

1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate. This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.

Chemical Properties

Crystalline

Uses

1-Aminocyclopropane-1-carboxylic Acid is a plant growth regulator. It is an NMDA agonist acting at the glycine site.

Definition

ChEBI: 1-aminocyclopropanecarboxylic acid is a non-proteinogenic alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position. It has a role as a plant metabolite and a member of ethylene releasers. It is a monocarboxylic acid and a non-proteinogenic alpha-amino acid. It is functionally related to a cyclopropanecarboxylic acid. It is a conjugate acid of a 1-aminocyclopropanecarboxylate. It is a tautomer of a 1-aminocyclopropanecarboxylic acid zwitterion.

Application

1-aminocyclopropanecarboxylic acid (ACC) is used in the following ways:
(1) Organic synthesis. It is used for the preparation of vinyls and for the formation of imine compounds by decarboxylation with triketones.
(2) Used as a substrate for the determination of ACC deaminase activity for the study of the growth-promoting effects of endophytic isolates obtained from fern roots and cucurbit seeds.
(3) Used as an ethylene precursor to study the effect of high ethylene concentration on lateral root density (LRD) in sorghum brown midrib (bmr) mutants.
(4) Used to study the effect of glycine on the antidepressant and anxiolytic effects of ACC in rats.

General Description

1-Aminocyclopropanecarboxylic acid is a member of 1-aminocycloalkanecarboxylic acids.

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1-Aminocyclopropanecarboxylic acid ,97% 1-Amino-1-cyclopropanecarboxylic acid ,98.5% 1-AMinocyclopropanecarbox... 1-AMino-1-cyclopropanecarboxylic acid, 99% 250MG 1-Aminocyclopropane-1-carboxylic acid 98% 1-AMino-1-carboxycyclopropane NSC 98430 1-AMinocyclopropane-1-carboxylic Acid, 95+% 1-Aminocyclopropanecarboxylic acid 1-Amino-1-cyclopropanecarboxylic acid 1-Aminocyclopropane-1-carboxylic acid, >=98% 1-Aminocyclopropane-1-carboxylic acid≥ 98% (Titration) Acpc-OH ACPC Carboxycyclopropylamine 1-amino-cyclopropanecarboxylicaci alpha-aminocyclopropanecarboxylicacid H-(1)NHCPROPN-OH CARBOXYCYCLOPROPYLAMINE 1-Aminocyclopropanecarboxylic acid(ACC) 1-AMINO-1-CYCLOPROPANECARBOXYLIC ACID 1-AMINOCYCLOPROPANECARBOXYLIC ACID 1,1-ACCP 1-AMINO-1-CYCLOPROPANECARBOXYLIC ACID, 9 7% Cyclopropanecarboxylicacid,1-amino-(6CI,7CI,8CI,9CI) H-ACC-OH.HCl a-Aminocyclopropanecarboxylic acid 1-AMINOCYCLOPROPANECARBOXYLIC ACID HYDROCHLORIDE (ACC, ACPC) 1-Amino-1-cyclopropanecarboxylic acid,99% 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem 1-Aminonecarboxylic acidcyclopropa 1-ACC ACID 1-AminocycL opropane-1-carboxyL 1-Aminocyclopropanecarboxylic Acid > 1-Aminocyclopropanecarboxylic acid USP/EP/BP Supply 1-Aminocyclopropanecarboxylic acid CAS 22059-21-8 1-Aminocyclopropanecarboxylic acid 22059-21-8 1-Ethyl-1H-pyrrole-2 AMinocyclopropanecarboxylic acid 1-AMinocyclopropane-1-carboxylate Cyclopropanecarboxylic acid, 1-amino- H-ACPC-OH ACC 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID Ac3c Fish acetyl CoA carboxylase (ACC) ELISA Kit 22059-21-8 2059-21-8 C4H7N1O2 Simple 3-Membered Ring Compounds Cyclopropanes Plant growth regulators Pesticides & Metabolites Pesticides Ion Channels Ionotropic Glutamate Receptor Modulators Ligand-Gated Ion Channels Chromatography Environmental Standards